Pharmacognosy (w/ Plant Chemistry) Flashcards
“The study of crude drugs”
A. Botany
B. Taxonomy
C. Pharmacology
D. Pharmacognosy
E. NOTA
D. Pharmacognosy
Laws of Hammurabi (172 BC); clay models of human body; medicinal effects of 250 plants
A. Babylonians
B. Egyptians
C. Indians
D. Germans
E. Greeks
A. Babylonians
A Greek physician wrote “De Materia Medica” in 78 A.D. in which he described about 600 plants that were known to have medicinal properties.
A. DIOSCORIDES
B. GALEN
C. CA Seydler
D. JA Schmidt
E. Emperor Shen Nung
A. DIOSCORIDES
Traditional medicine; “Science of life”; Mother of all healing arts
A. Babylonians
B. Egyptians
C. Indians
D. Germans
E. Greeks
C. Indians: Ayurveda
A Greek pharmacist- physician who lived in Rome, described the method of preparing formulas containing plant and animal drugs. “FATHER OF PHARMACY”
A. DIOSCORIDES
B. GALEN
C. CA Seydler
D. JA Schmidt
E. Emperor Shen Nung
B. GALEN
he coined the term, “pharmacognosy” from “pharmakon” and “gnosis” in Analecta Pharmacognistica
A. JA Schmidt
B. CA Seydler
C. F.A. Fluckiger
D. Friedrich serterne4
E. Shen nung
B. CA Seydler
used the word, “pharmacognosy”; Lehrbuch der Materia Medica
J.A Schimdt
Ensure the true natural source of drug (species to cultivate). Improper collection results to partial or complete substitution
A. Collection
B. Curing
C. Drying
D. Garbling
E. Harvesting
F. Packaging, Storage, Preservation
A. Collection
Sample gathering on specific or proper season (best time highest content); Manual labor vs. mechanical devices
A. Collection
B. Curing
C. Drying
D. Garbling
E. Harvesting
F. Packaging, Storage, Preservation
E. Harvesting
Remove moisture to prevent bacterial or fungal growth and enzymatic degradation
A. Collection
B. Curing
C. Drying
D. Garbling
E. Harvesting
F. Packaging, Storage, Preservation
C. Drying
Special drying process enhancing the properties of the plant’s active ingredient
A. Collection
B. Curing
C. Drying
D. Garbling
E. Harvesting
E. Packaging, Storage, Preservation
B. Curing
Removal of extraneous matter. Final step in the crude drug preparation
A. Collection
B. Curing
C. Drying
D. Garbling
E. Harvesting
E. Packaging, Storage, Preservation
D. Garbling
For protection and marketability (maintain quality). Heat at 65°C (simplest); fumigation with CH3Br; add a drop of CHCI3 or CCl4
A. Collection
B. Curing
C. Drying
D. Garbling
E. Harvesting
E. Packaging, Storage, Preservation
E. Packaging, Storage, Preservation
Are vegetable or animal drugs that consist of natural substances that have undergone only the process of collection and drying.
Any products that has not been advanced in value or improved in condition
Crude drugs
Natural substances
Crude drugs
Substances found in nature that comprise the whole plants and herbs and anatomic parts thereof
Crude drugs
Natural substances
Natural substances
This increases the weight of the drug
Moisture
This increases oxidation
Air
No definitive pharmacologic activity, their presence sometimes prevents the absorbability or potency of the active constituents.
INERT/INACTIVE CONSTITUENTS
constituents that may cause precipitation or other chemical changes in medicinal preparations.
A. PHARMACEUTICALLY ACTIVE
B. PHARMACOLOGICALLY ACTIVE
A. PHARMACEUTICALLY ACTIVE
responsible for the therapeutic activity of the drug, its either single chemical substances or mixtures of principle.
A. PHARMACEUTICALLY ACTIVE
B. PHARMACOLOGICALLY ACTIVE
B. PHARMACOLOGICALLY ACTIVE
Major source of energy, most abundant biomolecules on earth, main source of energy for all living organisms, serves as structural components.
A. Lipid
B. Carbohydrates
C. Amino acids
D. Resins
E. Proteins
B. Carbohydrates
Which type of sugar yields 2 monosaccharide molecules on hydrolysis?
A) Monosaccharides
B) Disaccharides
C) Trisaccharides
D) Tetrasaccharides
B) Disaccharides
Which type of sugar cannot be hydrolyzed to simple sugars?
A) Monosaccharides
B) Disaccharides
C) Trisaccharides
D) Tetrasaccharides
A) Monosaccharides
How many monosaccharide molecules are yielded on hydrolysis of trisaccharides?
A) 1
B) 2
C) 3
D) 4
C) 3
How many monosaccharide molecules are yielded on hydrolysis of tetraccharides?
A) 1
B) 2
C) 3
D) 4
D) 4
Which of the following are the three main monosaccharides in the human diet?
A) Glucose, galactose, and fructose
B) Glucose, sucrose, and fructose
C) Lactose, galactose, and fructose
D) Maltose, glucose, and fructose
A) Glucose, galactose, and fructose
Which monosaccharide is commonly known as “milk sugar”?
A) Glucose
B) Galactose
C) Fructose
D) Sucrose
B) Galactose
Which monosaccharide is commonly referred to as “blood sugar”?
A) Glucose
B) Galactose
C) Fructose
D) Sucrose
A) Glucose
Which monosaccharide is known for being the most water-soluble among sugars?
A) Glucose
B) Galactose
C) Fructose
D) Sucrose
C) Fructose
Which monosaccharide is commonly associated with fruits and is often called “fruit sugar”?
A) Glucose
B) Galactose
C) Fructose
D) Sucrose
C) Fructose
Which type of oligosaccharides are synthesized through the enzymatic connection of lactose?
A) Galactooligosaccharides
B) Human Milk Oligosaccharides
C) Fructooligosaccharides
D) Maltodextrins
A) Galactooligosaccharides
Which type of oligosaccharides are complex glycans found in breast milk?
A) Galactooligosaccharides
B) Human Milk Oligosaccharides
C) Fructooligosaccharides
D) Maltodextrins
B) Human Milk Oligosaccharides
What is the backbone of Human Milk Oligosaccharides?
A) Glucose
B) Fructose
C) Galactose
D) Disaccharide lactose
D) Disaccharide lactose
What type of bond links monosaccharides in oligosaccharides?
A) Peptide bond
B) Glycosidic bond
C) Phosphodiester bond
D) Disulfide bond
B) Glycosidic bond
Which carbohydrate polymer consists of 3-10 monosaccharides?
A) Polysaccharide
B) Oligosaccharide
C) Monosaccharide
D) Disaccharide
B) Oligosaccharide
Which of the following is NOT one of the most common disaccharides?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
D) Glucose
What is a disaccharide?
A) A carbohydrate formed by the condensation reaction of three simple sugars.
B) A carbohydrate formed by the condensation reaction of two simple sugars.
C) A carbohydrate formed by the hydrolysis reaction of two simple sugars.
D) A carbohydrate formed by the condensation reaction of four or more simple sugars.
B) A carbohydrate formed by the condensation reaction of two simple sugars.
Which disaccharide is commonly known as “table sugar”?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
A) Sucrose
What are the monosaccharides that make up sucrose?
A) Glucose + Fructose
B) Glucose + Galactose
C) Glucose + Glucose
D) Fructose + Galactose
A) Glucose + Fructose
Which disaccharide is commonly referred to as “milk sugar”?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
B) Lactose
What are the monosaccharides that make up lactose?
A) Glucose + Fructose
B) Glucose + Galactose
C) Glucose + Glucose
D) Fructose + Galactose
B) Glucose + Galactose
Which disaccharide is formed during the breakdown of starches?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
C) Maltose
What are the monosaccharides that make up maltose?
A) Glucose + Fructose
B) Glucose + Galactose
C) Glucose + Glucose
D) Fructose + Galactose
C) Glucose + Glucose
Which disaccharide is commonly found in germinating seeds such as barley and is produced when amylase breaks down starch?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
C) Maltose
Which disaccharide is commonly used to mask disagreeable tastes in troches and tablets?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
A) Sucrose
Which disaccharide is obtained by evaporating milk and is found in malted milk?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
B) Lactose
Which disaccharide is hydrolyzed by the specific enzyme lactase?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
B) Lactose
Which disaccharide is commonly used as a nutrient and a tablet diluent?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
C) Maltose
Which disaccharide is produced when glucose is caramelized?
A) Sucrose
B) Lactose
C) Maltose
D) Glucose
C) Maltose
Derived from the dried exudate of *Franxinus ornus *and is used as an osmotic diuretic and laxative in people with neurological trauma?
A) Mannitol
B) Sorbitol
C) Xylitol
D) Glucitol
A) Mannitol
Derived from the berries of mountain ash (Sorbus aucuparia) and is used in the manufacture of toothpaste and chewing gum?
A) Mannitol
B) Sorbitol
C) Xylitol
D) Glucitol
B) Sorbitol
alternative to sorbitol and is commonly used as a sugar substitute?
A) Mannitol
B) Sorbitol
C) Xylitol
D) Glucitol
C) Xylitol
Which of the following has a taste that is approximately half as sweet as sugar?
A) Mannitol
B) Sorbitol
C) Xylitol
D) Glucitol
B) Sorbitol
Which of the following is also known as D-glucitol?
A) Mannitol
B) Sorbitol
C) Xylitol
D) Glucitol
B) Sorbitol
Which of the following is used in people with neurological trauma as an osmotic diuretic and laxative?
A) Mannitol
B) Sorbitol
C) Xylitol
D) Glucitol
A) Mannitol
Component of buffer systems and is commonly used as an acidulant in effervescent formulations?
A) Cherry Juice
B) Citric Acid
C) Lactic Acid
D) Tartaric Acid
B) Citric Acid
Product of fermentation and undergoes the process of distillation to concentrate the alcohol content?
A) Cherry Juice
B) Citric Acid
C) Lactic Acid
D) Alcohol/Ethanol
D) Alcohol/Ethanol
Alcoholic beverages is derived from wine?
A) Brandy
B) Whiskey
C) Rhum
D) Diluted Alcohol
A) Brandy
Alcoholic beverages is made from malted grain?
A) Brandy
B) Whiskey
C) Rhum
D) Diluted Alcohol
B) Whiskey
A CNS depressant at high concentrations and a CNS stimulant at low concentrations?
A) Cherry Juice
B) Citric Acid
C) Lactic Acid
D) Alcohol/Ethanol
D) Alcohol/Ethanol
Alcoholic beverages is derived from molasses of Dil. Alcohol?
A) Brandy
B) Whiskey
C) Rhum
D) Diluted Alcohol
C) Rhum
A polysaccharide composed of long chains of glucose units and serves as a major energy storage molecule in plants?
A) Starch
B) Inulin
C) Dextran
D) Cellulose
A) Starch
A polysaccharide that consists of fructose units and is commonly found in plants as a storage carbohydrate?
A) Starch
B) Inulin
C) Dextran
D) Cellulose
B) Inulin
A polysaccharide formed by bacteria and is used in medical and industrial applications?
A) Starch
B) Inulin
C) Dextran
D) Cellulose
C) Dextran
A polysaccharide that forms the structural component of plant cell walls?
A) Starch
B) Inulin
C) Dextran
D) Cellulose
D) Cellulose
true about starch?
A) It is only found in animal cells
B) It is completely indigestible by humans
C) It is highly branched in structure
D) It is a protein-based molecule
C) It is highly branched in structure
starch preparation is chemically or mechanically processed to rupture all or part of the granules and is commonly used as a tablet binder?
A) Pregelatinized starch
B) Sodium starch glycollate
C) Hetastarch
D) Glutens
A) Pregelatinized starch
starch preparation is used as a disintegrating agent in pharmaceutical formulations?
A) Pregelatinized starch
B) Sodium starch glycollate
C) Hetastarch
D) Glutens
B) Sodium starch glycollate
Which starch preparation is a plasma expander and consists of more than 90-99% amylopectin?
A) Pregelatinized starch
B) Sodium starch glycollate
C) Hetastarch
D) Glutens
C) Hetastarch
Which component is a group of tacky proteins that impedes the flow of starch?
A) Pregelatinized starch
B) Sodium starch glycollate
C) Hetastarch
D) Glutens
D) Glutens
polymeric carbohydrate molecules composed of long chains of monosaccharide units bound together by glycosidic bond and on hydrolysis give the constituent monosaccharides or oligosaccharides.
A. Monosaccharide
B. Disaccharide
C. Oligosaccharide
D. Polysaccharide
D. Polysaccharide
Examples of polysaccharide:
SIDC
What are the criteria for a plant acid?
a) NMT 6C atoms and 2-3 carboxyl groups
b) NMT 4C atoms and 1-2 carboxyl groups
c) NMT 8C atoms and 3-4 carboxyl groups
d) NMT 10C atoms and 4-5 carboxyl groups
a) NMT 6C atoms and 2-3 carboxyl groups
Who isolated citric acid from lemon juice in 1784?
a) Louis Pasteur
b) Robert Boyle
c) Carl Wilhelm Scheele
d) Marie Curie
c) Carl Wilhelm Scheele
a by-product of the wine industry?
a) Citric acid
b) Tartaric acid
c) Lactic acid
d) Malic acid
b) Tartaric acid
In addition to being an acidulant in infant feeding formula, which acid is also used in feminine wash products like pH care®?
a) Citric acid
b) Tartaric acid
c) Lactic acid
d) Malic acid
c) Lactic acid
Linear/Helical 250-300 units 𝛂 -1,4
A. Amylose
B. Amylopectin
A. Amylose
Branched (every 25-30 mins) 1000 or more 𝛂-1,4 and 𝛂-1,6
A. Amylose
B. Amylopectin
B. Amylopectin
enzyme present in both pancreatic juice and saliva and is responsible for the breakdown of starches?
a) Alpha amylase
b) Beta amylase
c) Lipase
d) Protease
a) Alpha amylase
Which enzyme hydrolyses starch to nearly pure maltose?
a) Alpha amylase
b) Beta amylase
c) Lipase
d) Protease
b) Beta amylase
Besides its role in starch breakdown, what are the uses of beta amylase?
a) Tablet filler
b) Binder
c) Disintegrant
d) All of the above
d) All of the above
antidote for iodine poisoning?
a) Alpha amylase
b) Beta amylase
c) Lipase
d) Protease
b) Beta amylase
storage form of carbohydrates in animals and fungi?
a) Glycogen
b) Inulin
c) Dextran
d) Cellulose
a) Glycogen
Which polysaccharide is obtained from the subterranean organs of members of the family Compositae and is used in culture media as a fermentative identifying agent for certain bacteria?
a) Glycogen
b) Inulin
c) Dextran
d) Cellulose
b) Inulin
water-soluble polysaccharide of glucose is produced by the action of the transglucosylase enzyme system present in Leuconostoc mesenteroides?
a) Glycogen
b) Inulin
c) Dextran
d) Cellulose
c) Dextran
What are the uses of dextran?
a) Plasma expanders in cases of shock or pending shock caused by hemorrhage, trauma, or severe burns
b) Employed to reduce blood viscosity and improve microcirculation at low flow states
c) Both a) and b)
d) None of the above
c) Both a) and b)
What is the characteristic of cellulose?
a) Rigid, colorless, unbranched, and insoluble
b) Flexible, colored, branched, and soluble
c) Rigid, colored, unbranched, and soluble
d) Flexible, colorless, branched, and insoluble
a) Rigid, colorless, unbranched, and insoluble
main use of purified/absorbent cotton?
a) Surgical dressing
b) Coating agent
c) Water purification
d) Artificial tears
a) Surgical dressing
How is soluble guncotton/pyroxylin formed?
a) Action of nitric and sulfuric acid on cotton
b) Deacetylation of chitin
c) Hydrolysis of cellulose
d) Addition of castor oil and camphor to cotton
a) Action of nitric and sulfuric acid on cotton
What are the additional ingredients in soluble guncotton/pyroxylin and their purposes?
a) Castor oil (flexibility) and camphor (waterproofing)
b) Methyl cellulose and ethylcellulose (artificial tears)
c) Cellulose acetate phthalate (coating agent)
d) N/A
a) Castor oil (flexibility) and camphor (waterproofing)
What is the main application of chitosan?
a) Surgical dressing
b) Coating agent
c) Water purification
d) Artificial tears
c) Water purification
cellulose acetate phthalate (CAP)
a) Surgical dressing
b) Coating agent
c) Water purification
d) Artificial tears
b) Coating agent
methyl cellulose and ethycellulose
a) Surgical dressing
b) Coating agent
c) Water purification
d) Artificial tears
d) Artificial tears
What is the main function of chitin?
a) Water purification
b) Structural polysaccharides in animals
c) Coating agent
d) Artificial tears
b) Structural polysaccharides in animals
What is the primary role of chitin in animals?
A) Energy storage
B) Water absorption
C) Structural support
D) Enzyme synthesis
C) Structural support
process involved in the production of chitosan?
A) Acetylation of chitin
B) Dehydration of chitin
C) Deacetylation of chitin
D) Hydrolysis of chitin
C) Deacetylation of chitin
defining characteristic of heteroglycans?
A) They are composed of N Acetylglucosamine units
B) They result from the deacetylation of chitin
C) They yield multiple types of monosaccharide units upon hydrolysis
D) They are structural polysaccharides in animals
C) They yield multiple types of monosaccharide units upon hydrolysis
Natural plant hydrocolloids that can be classified as anionic or non-ionic polysaccharides or salts of polysaccharides?
a) Plant Gums
b) Plant Exudates
c) Both plant gums and plant exudates
d) None of the above
a) Plant Gums
Plant gum derived from Astragalus gummifer and belongs to the Leguminosae/Fabaceae family?
a) Tragacanth
b) Acacia
c) Karaya Gum
d) Sodium Alginate
a) Tragacanth
What are the primary components of tragacanth gum?
a) Bassorin and tragacanthin
b) Arabin and enzymes
c) D-galacturonic acid and D-glucuronic acid
d) Sodium salt of alginic acid
a) Bassorin and tragacanthin
Which plant gum is derived from Acacia Senegal and belongs to the Leguminosae/Fabaceae family?
a) Tragacanth
b) Acacia
c) Karaya Gum
d) Sodium Alginate
b) Acacia
What are the primary components of Acacia gum?
a) Bassorin and tragacanthin
b) Arabin and enzymes
c) D-galacturonic acid and D-glucuronic acid
d) Sodium salt of alginic acid
b) Arabin and enzymes
Which plant gum is derived from Sterculia urens or Cochlospermum gossypium?
a) Tragacanth
b) Acacia
c) Karaya Gum
d) Sodium Alginate
c) Karaya Gum
What are the primary components of Karaya gum?
a) Bassorin and tragacanthin
b) Arabin and enzymes
c) D-galacturonic acid and D-glucuronic acid
d) None of the above
c) D-galacturonic acid and D-glucuronic acid
Plant gum derived from Macrocystis pyrifera and belongs to the Lessoniaceae family?
a) Tragacanth
b) Acacia
c) Karaya Gum
d) Sodium Alginate
d) Sodium Alginate
What is the primary component of Sodium Alginate?
a) Bassorin and tragacanthin
b) Arabin and enzymes
c) D-galacturonic acid and D-glucuronic acid
d) Sodium salt of alginic acid
d) Sodium salt of alginic acid
Gelling component associated with red algae?
A) Kappa
B) Lota
C) Lambda
D) Mannuronic acid
E) A and B
E) A and B
Red Algae
A. Agar or Japanese Isinglass
B. Algin
C. Carrageenan or Irish Moss
D. Danish Agar
C. Carrageenan or Irish Moss