DDS Flashcards
A mixture of finely divided drugs or chemical in dry form; may be used internally or externally
Powder
8 sieve
Very coarse
20 sieve
Coarse
40 sieve
mod. Coarse
60 sieve
Fine
80 sieve
Very fine
The process of reducing the particle size of a solid substance to a finer state of subdivision.
Comminution
Substance is reduced to small particles by rubbing it in a mortar and pestle.
Trituration
Levigation
Pulverization by Intervention
Trituration
Substances are reduced and subdivided with an addition of material (ex. Solvent) that is easily removed after pulverization.
Trituration
Levigation
Pulverization by Intervention
Pulverization by Intervention
The particle size of the substance is reduced by adding a suitable nonsolvent to form a paste.
Trituration
Levigation
Pulverization by Intervention
Levigation
Common levigating agent
Mineral Oil
spatula is used to blend small amounts of powders on a sheet of paper or a pill tile.
Geometric dilution
Trituration
Tumbling
Spatulation
Sifting
Spatulation
mortar and pestle is used to reduce substance to small particles
Geometric dilution
Trituration
Tumbling
Spatulation
Sifting
Trituration
used when potent substances must be mixed with a large amount of diluent.
Geometric dilution
Trituration
Tumbling
Spatulation
Sifting
Geometric dilution
powders are mixed by passing them through sifters similar to those used to sift flour.
Geometric dilution
Trituration
Tumbling
Spatulation
Sifting
Sifting
the process of mixing powders in a large container rotated by a motorized process
Geometric dilution
Trituration
Tumbling
Spatulation
Sifting
Tumbling
Intended to be administered in dosage quantities that are
safe for the patient to measure.
Should pass through a 100-mesh sieve.
Dusting powders, aerosols, dentifrices, antacids, laxatives,
dietary nutrient supplements, douches
Bulk Powders
Divided Powders
Dusting Powders
Bulk Powders
Must be homogenous, free from potential of causing local
irritation.
Should flow easily, spread uniformly, and cling to the skin
upon application.
Generally dispensed in sifter-top containers
Bulk Powders
Divided Powders
Dusting Powders
Dusting Powders
(chartula, charts, powder papers, powders).
Single doses of the powdered drug mixture individually
enclosed in paper, cellophane, or metallic foil wrappers or
packets.
Sufficiently potent to require premeasured doses.
Bulk Powders
Divided Powders
Dusting Powders
Divided Powders
moisture resistant
Vegetable parchment
White bond
Glassine
Waxed
Vegetable parchment
moisture resistant properties
Vegetable parchment
White bond
Glassine
Waxed
White bond
moisture resistant
Vegetable parchment
White bond
Glassine
Waxed
Glassine
transparent waterproof paper (double wrap w/
white bond paper for protection from moisture)
Vegetable parchment
White bond
Glassine
Waxed
Waxed
Not intended for use with potent drugs because of
inherent error when a patient measures the dose with a teaspoon, scoop, etc.
Good for unstable drugs
Example: antibiotics for reconstitution
Granules