Pharmacogentics

Question 1

Personalized medicine has 3 important steps

Answer 1

Prevention
Diagnosis
Treatment

Question 2

Personalized medicine demand for

Answer 2

Safer, more effective drugs
Faster time to market
Cost-effective healthcare

Question 3

Factors which effect the drug response

Answer 3

Misdiagnosis
Age
Differences in disease severity
Presence of other diseases
Drug-drug interactions
Genetics

Question 4

Polymorphism

Answer 4

Variations in shape and form that distinguish normal individuals within a species from each other

Question 5

Types of polymorphism

Answer 5

Phenotypic
Biochemical
Chromosomal
DNA

Question 6

What is the most common type of DNA polymorphism in humans

Answer 6

SNPs — single nucleotide polymorphism

Question 7

2 types of variations

Answer 7

1- mutations — causes disease
2- polymorphism — risk factor, mostly no effect

Question 8

What is the biological marker that help scientists to locate genes that are associated with disease

Answer 8

SNPs

Question 9

Genetic variation that effects the drug response can be seen at different levels

Answer 9

Drug absorption
Drug distribution
Drug metabolism
Drug target receptor
Drug excretion

Question 10

Pharmacogenomics

Answer 10

Study of human genetic variability in relation to drug action and its application to medical treatment

Question 11

Pharmacogentics

Answer 11

Branch of pharmacology that examines the relation of genetic factors to variations in response to drugs

Question 12

Benefits of Pharmacogenomics

Answer 12

More powerful medications
More accurate methods or determining a drugs proper dose
Drugs that are safer and better the first time