Pharmacodynamics Notes

Question 1

The relationship between the concentration of a drug and the observed effect can be represented graphically as

Answer 1

Hyperbolic curve

Question 2

The response against the logarithm of the drug concentration transforms the D-R curve to a

Answer 2

Sigmoidal curve

Question 3

Drugs with similar MOA have

Answer 3

parallel curves

Question 4

Graded DRC relates does to

Answer 4

intensity of effect

Question 5

Quantal DRC relates does to

Answer 5

Frequency of effect

Question 6

All-or-none pharmacological effect is a feature of

Answer 6

Quantal Dose Response curve

Question 7

Fentanyl is a highly potent drug T/F

Answer 7

T

Question 8

Meperidine is a highly potent drug T/F

Answer 8

F

Question 9

Formula for Therapeutic index

Answer 9

Ti=LD50/ED50

Question 10

LD50

Answer 10

Median lethal dose of a drug in animals

Question 11

Types of antagonism

Answer 11

Pharmacological
Physiological
Chemical

Question 12

Drugs that are chemical antagonists

Answer 12

Dimercaprol and Mercuric ion

Question 13

Physiological antagonists

Answer 13

Histamine and adrenaline

Question 14

Types of pharmacological antagonists

Answer 14

Competitive
Non-competitive

Question 15

ACh and atropine are what type of antagonists

Answer 15

Competitive

Question 16

What type of antagonists are Epinephrine and Dibenamine

Answer 16

Non competitive