Noradrenaline Synthesis Storage Release Fate

Question 1

Exceptions to general rule of dual reciprocal innervation by the two branches of ANS

Answer 1

Most arterioles and veins (only sympathetic)
Most sweat glands (only sympathetic)
Salivary glands (innervated by both ANS divisions. Both stimulate salivary secretion)

Question 2

Mineralocorticoids are produced from what part of the adrenal gland

Answer 2

Cortex (Zona fasciculata)

Question 3

Catecholamines are produced from what part of the adrenal gland

Answer 3

Zona Reticularis

Question 4

Glucocorticoids are produced from where

Answer 4

Zona glomerulus

Question 5

The adrenal medulla releases Epinephrine and Norepinephrine into the blood by exocytosis of

Answer 5

Chromaffin Granules

Question 6

Concentration of L-tyrosine in plasma

Answer 6

1-1.5mg/dL

Question 7

Plasma ratio of norepinephrine to epinephrine

Answer 7

8:2

Question 8

Enzyme that converts Dopamine to Norepinephrine

Answer 8

Dopamine B-hydroxylase

Question 9

Enzyme that converts Norepinephrine to Epinephrine

Answer 9

Phenylethanolamine N-methyltransferase (PNMT)

Question 10

Tyrosine hydroxylase contains what cofactor

Answer 10

Fe2+ Tetrahydrobiopterin cofactor

Question 11

Tyrosine Hydroxylase activity is regulated by

Answer 11

Preganglionic nerves

Question 12

Cofactor of DOPA decatboxylase

Answer 12

Pyridoxal phosphate

Question 13

DOPA decarboxylase is stored in

Answer 13

Secretory vesicles

Question 14

End product of DOPA decarboxylase is located where

Answer 14

CNS

Question 15

Cofactor of Dopamine B-Hydroxylase

Answer 15

Cu; Vit C

Question 16

End product of DBH is located

Answer 16

in sympathetic nerves

Question 17

Methyl donor of PNMT

Answer 17

S-Adenosylmethionine

Question 18

Norepinephrine leaves the vesicle through

Answer 18

Passive Transport

Question 19

Epinephrine renters the secretory vesicle through

Answer 19

Active transport

Question 20

PNMT