Pharmacodynamics

Question 1

What the drug does to the body.

Answer 1

Pharmacodynamics

Question 2

______ is the receptor activator that stimulates an action.
(Parkinson’s can be treated by dopamine agonist drugs that bind receptors into the brain)

Answer 2

Agonist (activate)

Question 3

______ is a receptor blocker that prevents or cancels the action. (naloxone blocks opiate receptors to counteract opiate effects like morphine)

Answer 3

Antagonist (Anti-activate- block)

Question 4

_____ is the number that determines the safety of a drug.

• Divide the lethal dose by the effective dose.
• The bigger the number, the safer the drug.

Answer 4

Therepeutic Index (TI)

Question 5

______ is the amount needed to achieve the desired effect.

- The less amount, the more

Answer 5

Potency

Question 6

_____ is the maximal response obtained by a drug (Emax).

- There is no relationship with potency

Answer 6

Efficacy

Question 7

T/F - All adverse reactions are undesirable effects.

Answer 7

True

Question 8

Which type of allergic reaction is the most immediate and occurs within minutes or hours (anaphylactic shock)?

Answer 8

Type I

Question 9

What type of allergic reaction is the slowest reaction and occurs within hours or days (contact dermatitis).
- Unpredictable and not dose-related.

Answer 9

Type IV

Question 10

_______ act on non-target organs and are predictable and dose-related.

Answer 10

Side effects

Question 11

________ are a hypersensitivity reaction to a substance perceived as foreign and are unpredictable and NOT dose-related

Answer 11

Allergic effects