Pharmaceuticals Flashcards
the study of the way the body processes a drug to include how the drugs are absorbed, reach their site of action, are metabolized (physically and chemically changed) and exit the body
pharmacokinetics
the stud of the effects of drugs on the normal physiological functions of the body
pharmacodynamics
general principles of pharmacokenitics
absorption, metabolism, distribution, excretion
the process of movement from sit of adminstration into the circulatory system to provide desired effect
absorption
the means by which a drug travels from the bloodstream to the target tissue and site of action
distribution
the process by which the body transforms drugs into an inactive form that the body can excrete
metabolism
most drug metabolism occurs in the
liver
the elimination of drugs from the body after metabolization
excretion
are the cheif organs of excretion
kidneys
is the specific drug that treats a toxic effect
antidote
the action of a drug on cells is the
therapeutic effect
a drug that procedures and promotes the desired result
agnosit
a drug that prevents the agonist from acting
antagonist
identifies its chemical family
generic name
if a drug consists principally of one chemical it may be referred to by its
chemical name
given by the manufacture
trade names
purpose of the medication
usually drug binds to receptor sites on cells
therapeutic effect
predictable action or effect
related to the chemical and therapeutic characteristics of the medication
side effect
poisonous, potentially lethal
inadequate excretion, impaired metabolism, oversode, or drug sensitivity
toxic effect
overreaction, under-reaction or an unusual reaction from drugs
unknown cause unique to individuals
idiosyncratic effect
characteristic response to an allergen
prior sensitization to an initail dose of medication or one of its components
allergic response
responses to combined drugs that differ from their individual effects, may go far beyond the desired outcome
chemical or physiological drug interaction
synergistic (additive) effect
sets standards for control of drugs bot prescriptive and non-prescritive medication
includes strict rules concerning efficacy, purity, safety, and toxicity
US Food and Drug Administration (FDA)
drugs listed by both generic and trade names and according to their uses
medication reference published annually
physicians desk reference
