PHARMA (WELLS) Flashcards
Ultra- short Acting
- Thiopental ( Penthotal)
2. Methohexital (Brevital)
Short- Acting
- Secobarbital (Seconal)
2. Pentobarbital (Nembutal)
Intermediate Acting
- Amobarbital (Amytal)
2. Butabarbital (Butisol)
Long Acting
Phenobarbital (Luminal)
Nonbarbiturate sedative hypnotics
- Chloral hydrate
- Gluthethimiden (Doriden)
- Ethchlorvynol (Placidyl)
Common drug of abuse
Methaqualone (Quaalude)
DOC of termination of most convulsion of whatever origin
DIAZEPAM (Valium)
Reduces the duration of neuronal after discharge, stabilizes neuronal membrane & limits the spread of seizure activity
Phenytoin (Diphenylhydantoin)
Terminates LA induced seizures by an action on the amygdala portion of the limbic system
Diazepam (Valium)
Useful in trrminating certain cardiac arrythmias
Phenytois (Diphenylhydantoin)
Partial seizures
- Cortical focal (jacksonian)
- Temporal Lobe
- Psychomotor
Generalized seizures
- Absence (petit mal)
- tonic - clonic (grand mal)
- status epilepticus ( repeated tonic - clonic seizures)
Mainstay therapy in cortical focal & grand mal seizures
- Phenytoin (Dilantin)
- Phenobarbital ( Luminal)
Temporal Lobe & Psychomotor seizures
- Primidome (Mysoline)
- Phenytoin ( Dilantin)
Absence seizures
- Ethosuximide (Zarontin)
- Trimethadione ( Tridione)
Naturally occuring constituents of opium derived from the milky exudate of the unripe poppy plant
Morphine
Codeine
The gate in the gate control theory of pain as espoused by Melzack & Wall
Substantia Gelatinosa
Endogenous Opiods
Enkephalins & Endorphins
Most serious adverse effect of the opiods
Respiratory Depression
Opiods are relatively contrainidicates in px with
- Hypothyrodism
- Addison’s disease
- Asthma
- Px receiving concomitantly receiving other CNS depressant, MOA, Tricyclic depressants
Toxic effect of aspirin
Hypoprothrombinemic
Gastric Bleeding
DOC of Schizophrenia
- Antipsychotic agents (major tranquilizers)
- Phenothiazines
- Butyrophenones
Manic- Depressive Psychosis
Lithium Carbonate
Phenothiazines
