Anti-arryhthmic Drugs Flashcards

1
Q

Vaughn-williams Classification of Antiarrhythmic Drugs

A

Na
B
K
Ca

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2
Q

Class IA (Proclamation,Queen, Pyramid

A

Quinidine
Procainamide
Disopyramide

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3
Q

Class IB

A

Lidocaine

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4
Q

Tx. Ventricular Tachycardia

A

Lidocaine - safe

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5
Q

Class IC

A

Flecainide

Propafenone

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6
Q

Class II

A

Propanolol
Acebutalolol
Esmolol

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7
Q

Class III (K)

A

Amiodarone

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8
Q

Class IV (Ca)

A

Diltiazem, Verapamil

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9
Q

Adverse Effects Antiarrhythimic Drug

A

Bradycardia

Torsades de Pointes

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10
Q

NSAIDS are

A
all COX (prostaglandin)
anti-inflammatory
analgesics
anti-pyretic
cardiotoxic
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11
Q

Don’t prescribe NSAIDs in px with

A

Renal Failure

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12
Q

COX 1

A

Daily
Gastric Secretion
Platelet aggregation

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13
Q

COX 2

A

injury

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14
Q

Non- selective NSAIDS adverse effect

A

high gastric irritation

bleeding

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15
Q

Selective “COXIB” NSAIDS

A
less gastiric irritation
useful severe pain
not good px CDV (hypertension)
Risk : MI & Stroke
not exceed 1wk, Short as possible
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16
Q

Non- selective NSAIDS

A
  1. Ibuprofen
  2. Erodolac
  3. Meloxicam
  4. Naproxen
  5. Nabumetone
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17
Q

Least cardiotoxic NSAIDs

18
Q

Non selective COX 2 preferential

19
Q

Oldest NSAIDS

20
Q

Aspirin derived

A

Willow tree bark

21
Q

Aspirin

22
Q

Aspirin

23
Q

Aspirin activie form

A

Salicylates - COX inhibitor

24
Q

High dose of Aspirin

A

Salicylism- Sodium Bicarbonate

25
High dose of Aspirin complication
Ototoxicity
26
Aspirin should not be given in children
Reye Syndrome: Viral Infection , Fever, Children
27
Closure of Patent Ductus Arteriosus
Indomethacin | Ibuprofen
28
Opioid Analgesic
Mu receptors
29
Full agonist
``` Morphine Meperidine Heroin Methadone Fentanyl ```
30
Partial agonist
CODONE
31
Analgesics
1. Propoxyphene 2. Oxycodone 3. Hydrocodone 4. Tramadol
32
effect serotonin non addicting, regular prescription Adverse effect: Dull headaches Dizziness
Tramadol
33
Dextromethorphan / codeine
suppressing to urge to cough
34
Don't combine antitussive to mucolytics
high risk lower respiratory infection
35
Dont use loperamide or anti motility drug
infectious diarrheal
36
Primary management diarrhea
Oral rehydration
37
Partial agonist (punta na boyfriend)
Buprenorphine Pentazocine Nalbuphine
38
NAL
Opiod antagonist except: Nalbuphine (mixed anta & agonist)
39
Paracetamol not
Hepatotoxic not NSAIDS
40
Dangerous advers effecto of Opiods
Respiratory Depression
41
Papaver somniferum Scientific name
Opiods
42
Opiods adverse effects
smooth muscle relaxation