Pharma (1st Aid) Flashcards

1
Q

Tx. hypertension, angina, & arrythmias

A

CCBs

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2
Q

responsible for heart contraction & narrowing the arteries. its inhibition results in vasodilation of coronary & peripheral blood vessels & decreased comtraction

A

Calcium

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3
Q

Side effects Gningival hyperplasia & orthostartic hypotension

A

CCB

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4
Q

Cyclosporine

A

Immunosuppressant

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5
Q

Nifedipine

A

CCB

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6
Q

Phenytoin

A

Antiseizure

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7
Q

pril

A

ACE inhibitor

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8
Q

olol

A

Beta blockers

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9
Q

HMG-CoA reductase inhibitors (statins) that block the rate limiting step in cholesterol synthesis. Used to control hypercholesterolemia & coronary artery disease

A

Simvastatin

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10
Q

beta 2 adrenergic agonist. inhalatin to tx acute asthma attack

A

Albuterol, Isoproterenol

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11
Q

GERD (Heartburn), dyspepsia

A

Zollinger- Ellison Syndrome

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12
Q

tx GI upser associated with heartburn (dyspepsia) & acid indigestion

A

Antacids

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13
Q

decreased gastric secretions & decreased GI motility

A

Antimiscarinic drugs (atropine)

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14
Q

Used to tx acid- related GI conditions & work by blocking the H+/K+ AToase pumps on parietal cells that are directly responsible for secreting H+ ions into the stomach

A

Proton pump inhibitor (Omeprazole)

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15
Q

bacterium that is associated with gastritis, duodenal / stomach ulsers & stomach cancer including MALT lymphoma

A

H. Pylori

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16
Q

Is a chronic inflammatory condition that can affect the entire digestive system

A

Crohn’s Disease

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17
Q

artificial corticosteroid which would temporarily relieve symptoms of adrenal insufficiency

A

Hydrocortisone

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18
Q

mainly heart & lungs

A

Beta 1 & 2

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19
Q

beta 2 blocked

A

boronchoconstriction

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20
Q

nonselective beta blocker referred to as beta- adrenergic blocking agent, beta adrenergic antagonist or beta - antagonist. Used for hypertension, cardiac arrythmias , chest pain, migraine headaches & glaucoma

A

Propanolol

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21
Q

mixed alpa 1 & beta- blocker. Tx hypertension especially pregnancy induced hypertension

A

Labetalol

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22
Q

associated with pre- ecclampsia a condition in which there is increased protein in the urine (proteinuria)

A

Pregnancy Induced Hypertension (HTN)

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23
Q

Nonselective beta blockers

A

Nadolol & timolol

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24
Q

biphosphonate used to tx conditions of the bones such as osteoporosis, osteopenia, paget disease or hypercalcemia of malignancy

A

Zoledronic Acid

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25
Q

Side Effects of Biphosphonates

A

Irritation of esophagus (perforations) , risk of osteomecrosis

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26
Q

MOA of Erythomycin

A

Increased Bacterial Cell Permeability

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27
Q

Allergic to Penicillin

A

Erythromycin

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28
Q

metabolized largely in the liver by the CYP450

A

Rifampin

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29
Q

mucosal lesion caused by trauma., typically cheek biting

A

Linea Alba

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30
Q

associated with the herpes simplex virus

A

Perioral Vesicles

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31
Q

associated with the EBV

A

Hairy Leukoplakia

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32
Q

caused by cytotoxic cell- mediares hypersensitivity & sometimes associated with Hep. C. white lacy rash (Wickham’s striae)

A

Lichen Planus

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33
Q

Tricyclic Antidepressant

A

Imipramine & Amitriptyline

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34
Q

Antiplatelet. Analgesic, antipyretic to reduce fever & anti inflammatory,
Reye Syndrome

A

Aspirin (ASA)

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35
Q

nonselective cholinergic agonist

A

Pilocarpine

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36
Q

NSAIDS

A

Nabumetone

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37
Q

Indirect acting cholinergic agonist reversal agent atropine

A

Physostigmine

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38
Q

Adverse Effects of Anticholinergic Physostigmine

A

SLUDGE

  1. Salivation
  2. Lacrimatipn
  3. Urination
  4. Diarrhea
  5. GI clamping
  6. Emesis
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39
Q

Used in tx of chronic alcoholism by causing an acute sensitivity to alcohol

A

Disulfiram

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40
Q

major causes of the symptoms of a hangover

A

Acetaldehyde

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41
Q

Class of macrolide antibiotic that exert their effects by inhibiting bacterial protein synthesis

A

Clarithromycin

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42
Q

works by inhibiting bacterial protein synthesis

A

Clindamycin

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43
Q

Severe common adverse effect Clindamycin

A

Clostridium difficile associated diarrhea mosr frequent cause of pseudomembranous colitis

44
Q

Used in dentistry to tx periapical bony infections

A

Clindamycin concentrates in bone

45
Q

inhibition of bacterial protein synthesis

A

Doxycycline

46
Q

Adverse effects of doxycycline

A

Photosensitivity & discolorarion of teeth

47
Q

anti TB drug , hepatotoxicity

A

Rifampin

48
Q

mainly used as a memory & concentration enhancer & to tx circulatory disordes

A

Gingko Balboa

49
Q

improving recovery illneess well being tx erectile dysfunction , hepatitic C

A

Ginseng

50
Q

Used to tx or prevents colds or the flu by boosting the immune system

A

Echinacea

51
Q

Used to help mild to moderate depression

A

St. John’s Wort

52
Q

active ingrediern in chili peppers used in topical cream to relieve pain & itching

A

Capsaicin

53
Q

Selective Cox 2 inhibitor

A

Celecoxib

54
Q

Irreversible inhibitor of COX- 1, analgesic, antipyretic & antiinflammatory

A

Aspirin ( ASA)

55
Q

narcotic used as an analgesic agent & sometimes for its anti-tussive & anti- diarrheal properties

A

Codeine

56
Q

selective Cox- 2 inhibitor

A

Celecoxib

57
Q

Traditionsl NSAID inbhibt COX 1 & COX 2

A

Ibuprofen

58
Q

alpha- adrenergic blocker, causes vasodilation lowering the BP. aindicated for hypertension & benign prostate hyperplasia

A

Terazosin

59
Q

class of sulfonylurea drugs used in px with type II diabetes

A

Glipizide

60
Q

ACE

A

Lisinopril

61
Q

antipsychotic commonly used by px with bipolar disorder. serious renal & CNS toxicity

A

Lithium

62
Q

leukotriene receptor antagonist used for prophylactic & chrinic tx of asthma & seasonal allergies

A

Montelukast (singulair)

63
Q

DOC for tx of opiod overdose

A

Naloxone

64
Q

used to tx benzodiazepine overdose

A

Flumazenil

65
Q

tx high BP by stimulating alpha 2 receptors in the brain which result decrease in sympathetic tone

A

Clonidine

66
Q

Antifungal , IV

A

Amphotercin B

67
Q

Most potent antifungal

A

Griseofulvin

68
Q

Topical Antibiotics

A

Bacitracin
Polymycin B
Neomycin

69
Q

Most likely to cause an allergic reaction

A

Propoxycaine

70
Q

Lidocaine

A

Lignocaine, Xylocaine

71
Q

ester

A

Propoxycaine

72
Q

Prilocaine

A

Citanest

73
Q

Mepivacaine

A

Carbocaine

74
Q

Bupivacaine

A

Marcaine

75
Q

Vit. A

A

Reitnol

76
Q

Vit. B

A

Thiamine

77
Q

Vit C

A

Ascorbic

78
Q

Vit. D

A

Sunshine Vitamin

2-5 dihydrocholecalciferol

79
Q

Vit. K

A

Coagulation warfarin

80
Q

is a bezodiazepine that does not require phase 1 metabolism by the liver

A

Oxazepam

81
Q

rxn occur via oxidation, reduction , hydrolysis cyclization or decyclization reactioms

A

Phase I

82
Q

Phase 1 metabolism by the liver

A

Alprazolam
Midazolam
Triazolam
Diazepam

83
Q

non selective beta blocker that is contraindicated in px with COPD or asthma

A

Propanolol

84
Q

beta 1 selective blocker

A

Acebutolol, atenolol, esmolol, metorpolol, betaxolol

85
Q

diuretc can increase urination

A

Hydrochlorothiazide

86
Q

CCB

A

Diltiazem

87
Q

Ace inhibitor

A

Enalapril

88
Q

centrally acting alpha receptor agonist

A

Methyldopa

89
Q

peripherally acting alpha receptor blocking agent

A

Terazosin

90
Q

benzodiazepine antagonist used to td in the case of overdose

A

Flumazenil

91
Q

opiod receptor antagonist

A

Naloxone

Naltrexone

92
Q

antidote of heparin

A

Protamine

93
Q

tx of hyprperglycemia

A

Insulin

94
Q

beta lactamase resistant antibiotics

A

Piperacillin, carbenicillin & ticarcillin

95
Q

Gm (-) bacilli

A

Pseudomonas Aeruginosa

96
Q

used for rat poison

A

Warfarin

97
Q

Vit. K dependent fx

A

2, 7, 9, 10

98
Q

teratogenic

A

Warfarin

99
Q

warfacrin overdose

A

Vit+. K

100
Q

Use of acetaminophen

A

Hepatotoxicity

101
Q

used for abortion , labor induction, prevention of NSAID- induced gastric ulcers & maintenance of PDA in certain cardiac congenital defects

A

Misoprostol

102
Q

Influencing Bioavailability

A
Route
Degradatiom of drug prior to absorption
efficient Gastrointestinal absorption
Drug solubility
Hepatic 1st pass effect
Drug chemistry
103
Q

ACE inhibitors

A
  1. Cough
  2. edema
  3. Proteinuria
  4. Hyperkalemia
  5. Taste changes
  6. Orthostatic Hypotensi
  7. Fetal toxicity
  8. Rash
104
Q

Bactericidal antibiotiv that works by binding to penicillin- binding protein & blocking transpeptidase from crosslinking peptidyglycine in bacterial cell wall

A

Penicillin

105
Q

Antipseudomonal penicillin

A

Piperacillin
Carbenicillin
Ticarcillim

106
Q

Extended spectrum that is able to cover e.coli, haemophilus influenza, proteus mirabilis, listeria monocytogenes & salmonella

A

Amox