Pharm - Toxicities and Side Effects (Specific antidotes) Flashcards
Pg. 252 in First Aid 2014 Sections include: -Specific antidotes
What is the antidote/treatment for Acetaminophen toxicity?
N-acetylcysteine (replenishes glutathione)
What is the antidote/treatment for AChE inhibitors, Organophosphates toxicity?
Atropine followed by Pralidoxime
What is the antidote/treatment for Amphetamines (basic) toxicity?
NH4Cl (acidify urine)
What is the antidote/treatment for Antimuscarinic/Anticholinergic agents toxicity?
Physostigmine salicylate, Control hyperthermia
What is the antidote/treatment for Benzodiazepines toxicity?
Flumazenil
What is the antidote/treatment for Beta-blockers toxicity?
Glucagon
What is the antidote/treatment for Carbon monoxide toxicity?
100% O2, Hyperbaric O2
What is the antidote/treatment for Copper, arsenic, and/or gold toxicity?
Penicillamine
What is the antidote/treatment for Cyanide toxicity?
Nitrite + Thiosulfate, Hydroxocobalamin
What is the antidote/treatment for Digitalis toxicity?
Anti-dig Fab fragments
What is the antidote/treatment for Heparin toxicity?
Protamine sulfate
What is the antidote/treatment for Iron toxicity?
Deferoxamine, Deferasirox; “IRON, deFEroxamine, & deFErasirox”
What is the antidote/treatment for Lead toxicity?
EDTA, Dimercaprol, Succimer, Penicillamine
What is the antidote/treatment for Mercury, arsenic, and/or gold toxicity?
Dimercaprol (BAL), Succimer; Think: “MERCury & diMERCaprol”
What is the antidote/treatment for Methanol &/or ethylene glycol (antifreeze) toxicity?
Fomepizole > Ethanol, Dialysis