Pharm - Toxicities and Side Effects (Specific antidotes) Flashcards

Pg. 252 in First Aid 2014 Sections include: -Specific antidotes

1
Q

What is the antidote/treatment for Acetaminophen toxicity?

A

N-acetylcysteine (replenishes glutathione)

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2
Q

What is the antidote/treatment for AChE inhibitors, Organophosphates toxicity?

A

Atropine followed by Pralidoxime

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3
Q

What is the antidote/treatment for Amphetamines (basic) toxicity?

A

NH4Cl (acidify urine)

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4
Q

What is the antidote/treatment for Antimuscarinic/Anticholinergic agents toxicity?

A

Physostigmine salicylate, Control hyperthermia

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5
Q

What is the antidote/treatment for Benzodiazepines toxicity?

A

Flumazenil

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6
Q

What is the antidote/treatment for Beta-blockers toxicity?

A

Glucagon

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7
Q

What is the antidote/treatment for Carbon monoxide toxicity?

A

100% O2, Hyperbaric O2

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8
Q

What is the antidote/treatment for Copper, arsenic, and/or gold toxicity?

A

Penicillamine

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9
Q

What is the antidote/treatment for Cyanide toxicity?

A

Nitrite + Thiosulfate, Hydroxocobalamin

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10
Q

What is the antidote/treatment for Digitalis toxicity?

A

Anti-dig Fab fragments

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11
Q

What is the antidote/treatment for Heparin toxicity?

A

Protamine sulfate

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12
Q

What is the antidote/treatment for Iron toxicity?

A

Deferoxamine, Deferasirox; “IRON, deFEroxamine, & deFErasirox”

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13
Q

What is the antidote/treatment for Lead toxicity?

A

EDTA, Dimercaprol, Succimer, Penicillamine

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14
Q

What is the antidote/treatment for Mercury, arsenic, and/or gold toxicity?

A

Dimercaprol (BAL), Succimer; Think: “MERCury & diMERCaprol”

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15
Q

What is the antidote/treatment for Methanol &/or ethylene glycol (antifreeze) toxicity?

A

Fomepizole > Ethanol, Dialysis

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16
Q

What is the antidote/treatment for Methemoglobin toxicity?

A

Methylene blue, Vitamin C; Think: “METHemoglobin & METHylene blue”

17
Q

What is the antidote/treatment for Opioids toxicity?

A

Naloxone

18
Q

What is the antidote/treatment for Salicylates toxicity?

A

NaHCO3 (alkalinize urine), Dialysis

19
Q

What is the antidote/treatment for TCAs toxicity?

A

NaHCO3 (plasma alkalinization)

20
Q

What is the antidote/treatment for tPA, streptokinase, &/or Urokinase toxicity?

A

Aminocaproic acid

21
Q

What is the antidote/treatment for Warfarin toxicity?

A

Vitamin K, Plasma (if active bleeding)