Pharm- Nicotine cessation Flashcards
Nicotine- Indications
Smoking cessation- reduce withdrawal symptoms
Nicotine- MOA
Stimulates CNS
Nicotine- AE
Irritability, tremors, addition, physical dependance
Varenicline- Indications
Smoking cessation- fewer euphoric effects, blunts the reward center effects of nicotine if used
Varenicline- MOA
Partial receptor agonist
Varenicline- AE
Suicidal thoughts, vivid nightmares, mood changes
Buproprion- Indications
Smoking cessation- non nicotine based
Buproprion- MOA
Antidepressant- inhibits neuronal uptake of norepi and dopamine
Buproprion- AE
Dry mouth, HA, agitation
Naltrexone- Indications
Additive behavior cessation
Naltrexone- MOA
antagonizes opioid receptors
Naltrexone-AE
Insomnia, N/V anxiety, HA, abd pain