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HLK 3 > Pharm- Lung disease > Flashcards

Pharm- Lung disease Flashcards

1
Q

Short acting beta agonist- Indications

A
  • Asthma: Immediate relief of symptoms- most effective med for acute bronchospasm
  • Intermediate duration- 3-6 hrs
  • Only for use <2x/ week
    COPD: Long term use for bronchodilation
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2
Q

Short acting beta agonist- MOA

A

Relaxes bronchial smooth muscle- beta 2 agonist

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3
Q

Short acting beta agonist- AE

A
  • Nervousness, tremor, HA, palpitations
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4
Q

Short acting beta agonist- Names

A

Albuterol, levalbuterol, metaproternol

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5
Q

Long acting beta agonist- Names

A

salmeterol, formoterol

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6
Q

Long acting beta agonist- Indications

A
  • Long acting relief of symptoms- not control
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7
Q

Long acting beta agonist- MOA

A
  • Long acting beta agonist- relaxes bronchial smooth muscle
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8
Q

Long acting beta agonist- AE

A
  • Black box: Increased risk of death if used as long term controller
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9
Q

Mast cell stabilizers- Names

A

Cromolyn

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10
Q

Leukotriene modifiers- Names

A

montelukast, zafirlukast, zileuton

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11
Q

Leukotriene modifiers- Indications

A

Alternative controller for concern about steroids in children

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12
Q

Mast cell stabilizers- MOA

A

Inhibit inflammatory response of mast cells in lungs

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13
Q

Inhaled corticosteroids- Names

A

beclomethasone, fluticasone, triamcinolone

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14
Q

Inhaled corticosteroids- AE

A
  • Low side effect profile

- HPA axis may be suppressed in children, reducing growth

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15
Q

Anticholinergics- MOA

A

Block Ach to allow relaxation of bronchial smooth muscle

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16
Q

Anticholinergics- Names

A

ipatropium, tiotropium

17
Q

Anticholinergics- Indications

A

COPD- allows chronic bronchodilation

18
Q

Anticholinergics- AE

A
  • Dry mouth and oropharynx

- No systemic anticholinergic side effects

19
Q

Inhaled corticosteroids- Indications

A

Low dose- beginning at Asthma step 2

20
Q

Inhaled corticosteroids- MOA

A

Decrease underlying airway inflammation- eosinophils, marcophages, T- lymphocytes

21
Q

Mast cell stabilizers- AE

A

Irritation, dry throat, bitter taste

22
Q

Phosphodiesterase inhibitor- Theophylline- Indications

A

Alternative treatment in asthma/ COPD

23
Q

Phosphodiesterase inhibitor- Theophylline- MOA

A

Antagonizes adenosine receptors- increases cAMP

24
Q

Phosphodiesterase inhibitor- Theophylline- AE

A

N/V/HA insomnia

25
Q

Leukotriene modifiers- MOA

A

Blocks leukotriene pathway of inflammation

26
Q

Leukotriene modifiers- AE

A

HA, URI, fever, influenza sx, abd pain

27
Q

Systemic corticosteroids- Names

A

Dexamethasone, prednisone, solumedorl

28
Q

Systemic corticosteroids-Indications

A

Short- 5 days burst following acute exacerbation with incomplete/ poor response to albuterol

29
Q

Systemic corticosteroids-AE

A

HPA axis supression, cataracts, striae

HLK 3 (10 decks)

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