Pharm- Missed Questions, Includes all types of drugs Flashcards
Sumatriptan- use, side effects
Used for acute attacks of migraine
Expected side effects
Dizziness, vertigo
Tingling, warm sensation
Sumatriptan- contraindications
Ischecmic heart diseases
Coronary artery disease
Methimazole- action and uses
Blocks synthesis of thyroid hormones
Uses
Treats Graves’s Disease
Used prior to thyroid removal surgery
Emergency tx of thyrotoxicosis
Considered 1st line therapy
Methimazole- complications
Complications
Hypothyroidism (drowsiness, depression, weight gain, bradycardia, anorexia)
Agranulocytosis- Monitor for early signs of infection, fevers chills
Get blood count at baseline
Use filgrastim to treat agranulocytosis
Liver injury- monitor for hapatitis
Colesevelam- use/expected action
lower LDL cholesterol
May be used alone or with HMG-CoA reductase inhibitor like atorvastatin
Colesevelam- Complications and interactions
Constipation- client education to increase high fiber foods and oral fluids if not restricted
Interactions- bile-acid sequestrants interfere with absorption of levothyroxine, phenytoin, and absorption of fat soluble vitamins
Gemfibrozil- use
Purpose- decrease triglyceride levels (VLDL), increase HDL
Gemfibrozil complications
GI distress usually mild or self limiting
Gallstones- observe for RUQ pain and fat inolerance
Myopathy- obtain baseline CK levels, monitor CK levels, monitor for muscle aches, weakness, pain, tenderness, notify HCP if occur and stop med if CK levels are elevated
Hepatotoxicyt- obtain base line LFT and monitor
Neostigmine- action and use
Cholinesterase inhibitors prevent the enzyme cholinesterase from inactivating acetylcholine (ACh)
Uses
Treats myasthenia gravis
Alzheimer’s
Neostigmine Complications
Excessive muscarinic stimulation- increased GI motility, GI secretions, diaphoresis, increased salivation, bradycardia
Treat severe adverse effects with atropine
Cholinergic crisis
SLUDGE and the Killer B’s
Salivation, Lacrimation (crying), Urination, Diaphoresis/Diarrhea, GI cramping, Emesis, Bradycardia, Bronchospasm, Bronchorrhea
Nursing actions- have resuscitation equipment available, mechanical vent, administer atropine
Adrenal hormone replacement- Hydrocortisone purpose and use
Purposes- mimic effect of natural steroid hormone
Use- acute, or cronic replacement therapy for adrenocortical insufficiency (like addison’s disease, or adrenal crisis)
Adrenal hormone replacement- Hydrocortisone- complications and actions
Glucose intolerance- can increase plasma glucose causing hyperglycemia
Osteoporosis- take calcium supplements, impact exercise
Peptic ulcer/ GI discomfort- watch of coffee ground emesis, tarry stools, abdominal pain, notify HCP