Pharm-antihypertensive Flashcards
Ending of ace inhibitors
-pril
Ending of ARB’s
-sartan
Mechanism of action for ACE’s and ARBS
inhibits RAAS, body doesn’t retain fluid in kidneys, impacts loop of henle. RAAS system lets Na and water in and kick K+ out. Ace’s and arbs prevent this so Keep water out and lets potassium in.
This means they lower BP, not HR
Side effects of Aces and ARBS
Think AACE
- avoid with pregnancy
- angio edema
- Cough- for aces (dry hacking)
- elevated potassium
-Interact negatively with other drugs that affect potassium levels
What do Beta Blockers do
Lower HR and BP
Mechanism of action for Beta Blockers
Lowers HR and BP
Causes:
decrease resistance
Decrease workload
Decrease cardiac output
Which means bad for patients with acute, or worsening heart failure
Beta Blockers Side Effects
Think 3 B’s
Bradycardia, and Blood Sugar Masking
Bradycardia
Hold for HR less than 60, or BP systolic less than 100, or MAP less than 60
Slow position changes
Breathin problems
Wheezing
Bad for HF patients
Can worsen HF patients
Look for
New Edema
Worsening crackles
Rapid weight gain
New JVD
Always report to HCP
Blood sugar masking
Sugars below 70
Hide cool, shaky, clammy, even hides increased HR
Calcium Channel Blockers end with
-dipine, (nifedipine) cardizem and verapamil
What doe CCB’s do
calms heart, lowers BP and HR
Nifedipine
Think declines the HR, not BP
Diltiazem
Like “zen yoga”
Relaxes BP and HR
Verapamil
“Calm and chill”
Lowers BP and HR
Works by relaxing blood vessles, making it easier to pump blood
CCB nursing considerations
Count HR and BP before giving
Change positions slowly- prevent orthostatic hypotension
Bad headaches are normal
What does Digoxin do? Why give it
-digs for deeper contraction, increases contractility
- given for systolic HF
- negative chronotropic- decreases HR, not BP
Top signs of Digoxin toxicty
Over 2.0
Early signs are vision changes or blurred vision and nausea and vomiting
Nursing considerations for Dig
Older patients and decreased kidney function increased risk for toxicity
Any patient with creatinine over 1.3, means kidney injuree
Potassium- low potassium, below 3.5, increases risk for dig toxicity
At risk is anyone taking thaizide or loop diuretics
- Must check apical pulse for 60 seconds before giving
Dilators
Given for chest pain, and HF patients to lower BP
Open up blood pressure to decreased BP and decrease resistance
Lowers preload and afterload
Top 5
Nitroglycerin
Nitroprusside
Hydralazine
Isosobride
Minoxidil
precautions for dilators
No viagra- drugs ending in -afil, sildenafil
Stop nitro if systolic lower than 100