Pharm: Insulin Flashcards

1
Q

What does insulin do?

A

LOWERS blood sugar

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2
Q

______ is low blood sugar

A

Hypoglycemia

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3
Q

______ is high blood sugar

A

Hyperglycemia

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4
Q

What is the chronic disease that results from deficient glucose metabolism? Unable to move glucose (sugar) into cells to be used for energy (sugar will stay and accumulate in blood)

A

Diabetes Mellitus

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5
Q

What is the NORMAL blood glucose range?

A

70-110

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6
Q

What are the 3 MAJOR symptoms of HYPERGLYCEMIA (3P’s)?

A

Polyuria, Polydipsia, and Polyphagia

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7
Q

What is Polyuria?

A

frequent need to urinate (filter out sugar)

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8
Q

What is Polydipsia?

A

thirsty (dilute the blood)

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9
Q

What is Polyphagia?

A

increased appetite (sugar is not moving into cells, so body cannot convert the sugar into energy to use)

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10
Q

What is the #1/first sign of type 1 diabetes?

A

Weight loss

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11
Q

Type 1 diabetics require _____ ____ (lifelong)

A

exogenous (from outside of the body) insulin

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12
Q

What can the pancreas of the type 1 diabetic not do?

A

the pancreas does not secrete insulin

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13
Q

When is type 1 diabetes usually diagnosed?

A

childhood/adolescence

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14
Q

When is type 2 diabetes usually diagnosed?

A

adulthood (but can happen in younger)

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15
Q

What is type 2 diabetes?

A

the pancreas still secretes insulin, but not enough or tissues are no longer sensitive to the insulin

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16
Q

What is Secondary Diabetes?

A

diabetes due to medications

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17
Q

What are the medications that can cause Secondary Diabetes?

A

glucocorticoids, thiazide diuretics, and epinephrine

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18
Q

When and why does Gestational Diabetes occur?

A

during pregnancy because of hormonal changes

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19
Q

Where is insulin released from?

A

beta cells of islets of Langerhans in the pancreas

20
Q

Why is insulin secreted?

A

in response to the increase in blood glucose

21
Q

What med are type 1 diabetics placed on?

A

exogenous insulin

22
Q

What med are type 2 diabetics placed on?

A

oral antihyperglycemics or oral antidiabetics (sometimes placed on exogenous insulin)

23
Q

A lab value used to determine how well a patients diabetes is controlled over 3 MONTHS

A

Hemoglobin A1c

24
Q

What should a nondiabetic’s A1c be?

A

less than 6

25
What should a well controlled diabetic patient's A1c be?
less than 7
26
What do you need to know about each different type of insulins?
onset, peak, duration
27
What does ONSET mean?
when effects are seen
28
What does PEAK mean?
when effects are the greatest (highest concentration)
29
What does DURATION mean?
the length of time the medication produces its desired therapeutic effect
30
When could a patient taking insulin be HYPOglycemic?
during the peak
31
How is insulin currently manufactured?
by using deoxyribonucleic acid (DNA) technology
32
Where is insulin stored?
in the refrigerator (usually long acting) or at room temperature
33
What are the different types of insulin?
Rapid-acting Short-acting Intermediate-acting Long-acting Combinations
34
What *color* is Rapid-acting insulin?
clear
35
What *color* is Short-acting insulin?
clear (Humulin R)
36
What *color* is Intermediate-acting insulin?
cloudy (NPH)
37
How to mix different insulins?
go from clear to cloudy (not contaminating clear)
38
What can cause insulin resistance?
animal insulin and obesity
39
Promote use of glucose by body cells, store glucose as glycogen in muscles
the ACTION of insulin
40
What is the USE of insulin?
reduce blood glucose and control diabetes mellitus
41
What meds decrease glucose?
TCAs, MAOIs, aspirin, oral anticoagulants
42
_______ insulin is adjusted doses dependent on individual blood glucose
Sliding-scale
43
When to monitor blood glucose?
before meals and at bedtime (rapid or short acting)
44
______ is when SubQ tissue becomes hard from trauma/continuous use of injection site
Lipodystrophy
45
What would be given with HYPOglycemia?
glucagon
46
Methods of insulin administration
pens pumps jet injectors