Pharm Formulas Flashcards
1
Q
Volume of Distribution
A
Vd = A/C
2
Q
First Order Elimination Formulas
A
C= C0 * e^-ket A = dose * e^-ket
3
Q
Elimination Half-life Formula
A
t1/2= 0.7/ke t1/2= (0.7* Vd)/CL
4
Q
Clearance
A
CL= Vd * Ke
5
Q
Rate of elimination
A
=CL *C
6
Q
Rate of infusion ss
A
= CL * Css
7
Q
Amount in body ss
A
= Vd * Css
8
Q
Maintenance dose
A
Dm= CL *Css OR Dm= ke * Vd * Css
9
Q
intermittent doses
A
Dm rate =CL *Css * dosing interval
10
Q
Maximum maintenance dose
A
D M,max = (Vd/F) (Cupper-Clower)
11
Q
Dosing interval
A
(τ)= ln(Cupper/Clower)/ke
12
Q
Loading dose
A
= Vd * desired plasma concentration
13
Q
Bioavailability
A
F= Area under the curve (route)/ Area under the curve (IV)
