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1. Exams - Semester 3 > Pharm - Exam 2 > Flashcards

Pharm - Exam 2 Flashcards

1
Q
  1. Hyperprolactinemia DA antagonism is due to what tract?
A

Infundibular

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2
Q
  1. Sedative SE of TCA due to blocking of what receptors?
A

H1

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3
Q
  1. Pt started on med has dry everything - aka anticholinergic SE - what drug did they most likely get?
A

Doxepin (TCA)

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4
Q
  1. Difference between a FGA and an SGA?
A

SGA doesn’t cause TD

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5
Q
  1. SGAs have what in common?
A

Block 5HT receptors

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6
Q
  1. What would you need to monitor every 6 months when they start an antipsychotic?
A

AIMS

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7
Q
  1. What would be the reason to start a pt on a LONG ACTING IM antipsych?
A

Non compliant pt

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8
Q
  1. What would be a reason to start a pt on an IMMEDIATE ACTING IM antipsych?
A

Acute agitation

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9
Q
  1. What drug would most likely cause pseudoparkinsonism?
A

Haldol (FGA), All other choices were SGAs

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10
Q
  1. How would you tx acute dystonia?
A

IM benztropine

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11
Q
  1. How would you tx akathisia?
A

PO Propranolol

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12
Q
  1. How would you tx pseudoparkinsonism?
A

PO Benadryl

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13
Q
  1. MOA of BZDs?
A

Enhance GABA activity

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14
Q
  1. What would you want to monitor with clozapine?
A

Wt changes, WBC, ANC

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15
Q
  1. Which agent do you have to take with meals?
A

Ziprasidone

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16
Q
  1. Which drug causes GI distress, sex dysfxn & insomnia?
A

Citalopram

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17
Q
  1. Which would not cause discontinuation syndrome?
A

Fluoxetine

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18
Q
  1. Which of the follow doesn’t act on 5HT reuptake?
A

Buproprion

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19
Q
  1. What would you have to do to start a pt on an MAOI who has been taking fluoxetine?
A

d/c fluoxetine & wait 5 wks to start MAOI

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20
Q
  1. Whats the MOA of tranylcypromine?
A

MAO-I

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21
Q
  1. Pt has hx of wgt gain & DM what would you NOT want to start them on?
A

Olanzapine

22
Q
  1. Pt has been on clozapine for 6 months and just recently had ataxia, seizure what mostly likely happened?
A

The pt stopped smoking 3 wks ago

23
Q
  1. Why are SSRIs (Sertraline) 1st line compared to TCAs (Imipramine)?
A

No fatality in overdose in SSRIs

24
Q
  1. Lady with classic MDD, what do we wanna give her?
A

Sertraline

25
Q
  1. Whats the MOA of duloxetine?
A

Mixed 5HT & NE reuptake inhibitor

26
Q
  1. Pt has a history of seizures what would we NOT want to give them?
A

Bupropion

27
Q
  1. What is true of buspirone?
A

Onset in 7-10 days

28
Q
  1. Which one would most likely cause hypersomnolence, tough time waking up, aka HANGOVER effect?
A

Diazepam

29
Q
  1. Best BZD for elderly?
A

Lorazepam

30
Q
  1. MOA of remelteon?
A

Melatonin agonist

31
Q
  1. MOA of suvorexiant?
A

Orexin antag

32
Q
  1. MOA of paroxetine?
A

SSRI

33
Q
  1. Remelteon what is it used for?
A

Falling asleep ONLY

34
Q
  1. MOA of diphenhydramine?
A

Anti-Histamine

35
Q
  1. What do you wanna tell everyone with a sleeping problem?
A

GET YOUR SLEEP HYGIENE

36
Q
  1. Why are benzos not 1st line for txing sleep/anxiety?
A

They get tolerance within 2 wks

37
Q
  1. What drug do you wanna give someone with hepatic dysfxn for mood ctrl?
A

Lithium

38
Q
  1. Lithium plus NSAID does what?
A

INCREASES the concentration of Lithium

39
Q
  1. Lithium plus caffeine does what?
A

DECREASES the conc of lithium

40
Q
  1. VPA plus CBZ does what?
A

Decreases the conc of VPA

41
Q
  1. What tract is basically tx of positive sxs?
A

Mesolimbic and mesocortical

42
Q
  1. Pt has BPD what do we wanna do to prevent a depressive episode?
A

Lamotrigine

43
Q
  1. Pt on lamotrigine what do we wanna monitor?
A

Rash

44
Q
  1. Pt on lamotrigine and gonna put them on VPA what do u have to do?
A

Decrease lamotrigine by 50%

45
Q
  1. Which one do u wanna give a pt who has a mixed manic episode?
A

VPA

46
Q
  1. When do you check the drug level of lithium?
A

Immediately before am dose (bc it’s a 8-10 hrs s/p dose trough level)

47
Q
  1. Which is a partial DA agonist?
A

Aripiprazole

48
Q
  1. VPA what do you wanna order?
A

Liver & VPA serum concentration

49
Q
  1. Pt has hypothyroidism what drug are they most likely on?
A

Lithium

50
Q
  1. Tyramine diet affects what drug?
A

Phenylzine

1. Exams - Semester 3 (21 decks)

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