pharm drugs Flashcards
name the beta lactam antibitocs
pencillin
amoxicillin
cephalosporins
-cefadroxil
-cephalexin
3 alternative if immediate type 1 hypersensitivity to penicillin
azirhtomycine or clarithromycin (both macrocodes)
clindamycin (lincsamides)
what is the suffix for a penicillin alternative to immediate allergy
mycin
azirhtomycine or clarithromycin (both macrolides)
clindamycin (lincsamides)
what bacteria is penicillin for
group a streptococcal pharyngitis
3 bacteria causing acute otitis media
- streptococcus pneumonia
- haemophilus influenza a
- mortadella catarrhalis
what to do in antibiotic resistance for acute otitis media
for strep pneumonia doeuble the dose of amoxicillin
for m catarrhalis and h influenza do amoxicillin plus clavulanate (beta lactase inhibitor)
what are the 2 analgesics that help w pain
acetaminophen (Tylenol)
ibuprofen (Advil)
Advil is aka
ibuprofen
tylenol is aka
acetaminophen
what do you use for derm cases
corticosteroids
1. glucocorticoids
2. mineralocorticoids
what do 1. glucocorticoids
2. mineralocorticoids work on
- proftein, fat, carb metabolism
- electrolytes
derm what is the action of drugs
vasoconstriction, anti mitotic (cell divide), immunosuppression, anti inflam and reduce pro inflam cytokines
low med and high potency corticosteroids for which areas
low- face and skin folds
med- body and scalp
hihg- palms and soles
which NSAID is cox 2 inhibitor
celecoxib
h NSAIDS do COX1 and COX2
acetylsalicylic acids (ASA) *(aspirin)
ibuprofen (Advil)
what type of binding is aceytlysalyclic acid
irreversible inhibition; non competitive binding
what inhibits COX3 (not an anti inflam)
acetaminophen (Tylenol)
acetaminophen (*tylenol) vs ibuprofen (Advil) vs acetylysalyclic acid (aspirin)
acetaminophen is a COX3 inhibitor
ibuprofen and ASA are COX1/ anti inflmmatory/ NSAIDS
acetamiphin and ibuprofen are for pain (analgesic)
gastroprotection when using NSAIDs
- use cox2 selective (celecoxib)
- use prostaglandin analogues; misoprostol
- use proton pump inhibitors: omeprazole
gaba derivatives
name 2 and what they act on
pregabalin
gabapentin
act on Ca2+ v gated channels
give antispasmodics (2 classes)
ang an example of antispastic
antispasmodic
-benzodiazepenes(clonozepem)
-non benzodiapenze (methocarbomal)
anti spastic (baclofen)
antispastic
baclofen
non benzo antispasmodic
methocarbamolq
what do anti spastics work on
beta subunit of GABA receptor ; k+ influx and decrease ca2+
3 categories of antidepressants
TCA
SSRI
SNRI
example of TCA
imipramine
SSRI
escitalopramS
SNRI
venlafaxine
TCA
SSRI
SNRI
imipramine
escitolaprm
venlafaxine
benzodiazepines example and what it works on
clonazepam and works on GABA A receptor
benzo uses
anxiety and muscle relax
