Pharm drug rxn

Question 1

coronary vasospasm

Answer 1

cocaine
sumatriptan
ergot alkaloids

Question 2

cutaneous flushing

Answer 2

vancomycin
adenosine
niacin
Ca channel blockers

Question 3

torsades de pointes

Answer 3

class III (sotalol) and class IA (quinidine) antiarrhythmics

Question 4

agranulocytosis

Answer 4

clozapine
carbamazepine
colchicine
propylthiouracil
methimazole
dapsone

Agranulocytosis Could Certainly Cause Pretty Major Damage

Question 5

aplastic anemia

Answer 5

chloramphenicol
benzene
NSAID
propylthiouracil/methimazole

Question 6

direct coombs positive hemolytic anemia

Answer 6

methyldopa

penicillin

Question 7

hemolysis in G6PD deficient pts

Answer 7

isoniazid
sulfonamides
primaquine
aspirin
ibuprofen
nitrofurantoin

Question 8

megaloblastic anemia

Answer 8

phenytoin
methotrexate
sulfa drugs

Question 9

cough

Answer 9

ACE-I

Question 10

pulmonary fibrosis

Answer 10

bleomycin
amiodarone
bulsulfan

Question 11

acute cholestatic hepatitis, jaundice

Answer 11

erythromycin

Question 12

Hepatic necrosis

Answer 12

Halothane
Amanita phalloides
Valproic acid
acetaminophen

Question 13

Hepatitis

Answer 13

INH

Question 14

gynecomastia

Answer 14

spironolactone
digitalis
cimetidine
alcohol use
ketoconazole

Question 15

hot flashes

Answer 15

tamoxifene

clomiphene

Question 16

hyperglycemia

Answer 16

niacin
tacrolimus
protease inhibitors
HCTZ
corticosteroids

Question 17

hypothyroidism

Answer 17

lithium
amiodarone
sulfonamides

Question 18

Fat redistribution

Answer 18

glucocorticoids

protease inhibitors

Question 19

gingival hyperplasia

Answer 19

phenytoin

verapamil

Question 20

gout

Answer 20

furosemide
thiazide
niacin
cyclosporine

Question 21

osteoporosis

Answer 21

corticosteroids

heparin

Question 22

myopathies

Answer 22

fibrates
niacin
colchicine
hydroxychloroquine
Interferon-a
penicillamine
statins
glucocorticoids

Question 23

photosensitivity

Answer 23

sulfonamides
amiodarone
tetra

Question 24

SLE syndrome

Answer 24

hydralazine
INH
Procainamide
Phenytoin

Question 25

Stevens Johnson syndrome

Answer 25

``` penicillin ethosuximide carbamazepine sulfa drugs lamotrigine allopurinol phenytoin phenobarbital ```

Question 26

diabetes insipidus

Answer 26

lithium | demeclocycline

Question 27

fanconi's syndroe

Answer 27

old tetracycline

Question 28

hemorrhagic cystitis

Answer 28

cyclophosphamide ifosfamide (prevent with mesna)

Question 29

interstitial nephritis

Answer 29

methicillin NSAIDs furosemide

Question 30

SIADH

Answer 30

carbamazepine | cyclophosphamide

Question 31

parkinson sx

Answer 31

antipsychotics reserpine metoclopramide

Question 32

seizures

Answer 32

``` isoniazid buproprion imipenem tramadol enflurane metoclopramide ```

Question 33

anti-cholinergic effets

Answer 33

atropine TCAs H1 blockers neuroleptics

Question 34

disulfiram

Answer 34

metronidazole 1st gen sulfonylureas cephalosporins

Question 35

nephrotoxicity

Answer 35

aminoglycosides vancomycin loop diuretics cisplatin