Pharm drug rxn Flashcards

1
Q

coronary vasospasm

A

cocaine
sumatriptan
ergot alkaloids

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2
Q

cutaneous flushing

A

vancomycin
adenosine
niacin
Ca channel blockers

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3
Q

torsades de pointes

A

class III (sotalol) and class IA (quinidine) antiarrhythmics

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4
Q

agranulocytosis

A
clozapine
carbamazepine
colchicine
propylthiouracil
methimazole
dapsone

Agranulocytosis Could Certainly Cause Pretty Major Damage

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5
Q

aplastic anemia

A

chloramphenicol
benzene
NSAID
propylthiouracil/methimazole

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6
Q

direct coombs positive hemolytic anemia

A

methyldopa

penicillin

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7
Q

hemolysis in G6PD deficient pts

A
isoniazid
sulfonamides
primaquine
aspirin
ibuprofen
nitrofurantoin
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8
Q

megaloblastic anemia

A

phenytoin
methotrexate
sulfa drugs

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9
Q

cough

A

ACE-I

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10
Q

pulmonary fibrosis

A

bleomycin
amiodarone
bulsulfan

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11
Q

acute cholestatic hepatitis, jaundice

A

erythromycin

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12
Q

Hepatic necrosis

A

Halothane
Amanita phalloides
Valproic acid
acetaminophen

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13
Q

Hepatitis

A

INH

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14
Q

gynecomastia

A
spironolactone
digitalis
cimetidine
alcohol use
ketoconazole
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15
Q

hot flashes

A

tamoxifene

clomiphene

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16
Q

hyperglycemia

A
niacin
tacrolimus
protease inhibitors
HCTZ
corticosteroids
17
Q

hypothyroidism

A

lithium
amiodarone
sulfonamides

18
Q

Fat redistribution

A

glucocorticoids

protease inhibitors

19
Q

gingival hyperplasia

A

phenytoin

verapamil

20
Q

gout

A

furosemide
thiazide
niacin
cyclosporine

21
Q

osteoporosis

A

corticosteroids

heparin

22
Q

myopathies

A
fibrates
niacin
colchicine
hydroxychloroquine
Interferon-a
penicillamine
statins
glucocorticoids
23
Q

photosensitivity

A

sulfonamides
amiodarone
tetra

24
Q

SLE syndrome

A

hydralazine
INH
Procainamide
Phenytoin

25
Q

Stevens Johnson syndrome

A
penicillin
ethosuximide
carbamazepine
sulfa drugs
lamotrigine
allopurinol
phenytoin
phenobarbital
26
Q

diabetes insipidus

A

lithium

demeclocycline

27
Q

fanconi’s syndroe

A

old tetracycline

28
Q

hemorrhagic cystitis

A

cyclophosphamide
ifosfamide
(prevent with mesna)

29
Q

interstitial nephritis

A

methicillin
NSAIDs
furosemide

30
Q

SIADH

A

carbamazepine

cyclophosphamide

31
Q

parkinson sx

A

antipsychotics
reserpine
metoclopramide

32
Q

seizures

A
isoniazid
buproprion
imipenem
tramadol
enflurane
metoclopramide
33
Q

anti-cholinergic effets

A

atropine
TCAs
H1 blockers
neuroleptics

34
Q

disulfiram

A

metronidazole
1st gen sulfonylureas
cephalosporins

35
Q

nephrotoxicity

A

aminoglycosides
vancomycin
loop diuretics
cisplatin