Pharm Chapter 43- Histamine Flashcards

1
Q

What drugs are ethanolamines (1st generation)

A

Diphenhydramine, carbinoxamine, clemastine, dimenhydrinate

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2
Q

What drugs are ethylenediamines (1st generation)

A

Pyrilamine, tripelennamine

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3
Q

What drugs are alkylamines (first generation)

A

Chlorpheniramine, brompheniramine

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4
Q

What drugs are piperidines (1st generation)

A

Cyproheptadine, phenindamine

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5
Q

What drug is a phenothiazine (1st generation)

A

Promethazine

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6
Q

What drugs are piperazines (1st generation)

A

Hydroxyzine, cyclizine, meclizine

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7
Q

What drug is a tricyclic dibenzoxepins (1st generation)

A

Doxepin

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8
Q

What drugs are piperazines (second generation)

A

Cetirizine

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9
Q

What drug is alkylamine (2nd generation)

A

Acrivastine

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10
Q

What drugs are second generation piperidines

A

Loratadine, desloratadine, levocabastine, ebastine, mizolastine, fexofenadine

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11
Q

What drugs are second generation phthalzinones

A

Azelastine

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12
Q

What are the contraindications for diphenhydramine

A

Newborns or premature infants, nursing mothers

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13
Q

What are the contraindications for carbinoxamine

A

Acute asthma attach, MAOI therapy, narrow-angle glaucoma, PUD, severe coronary artery disease, severe hypertension, urinary retention

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14
Q

What are the contraindications for clemastine

A

Lactation, lower respiratory symptoms, MAOI therapy, newborn/premature infants

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15
Q

What are the contraindications for tripelennamine

A

Narrow-angle glaucoma, stenosing peptic ulcer, symptomatic prostatic hypertrophy, bladder neck obstruction, pyloroduodenal obstruction, lower respiratory tract symptoms, premature infants, neonates, nursing mothers, concomitant therapy with MAO inhibits

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16
Q

What are the contraindications for brompheniramine

A

Concurrent MAOI therapy, focal CNS lesions

17
Q

What are the contraindications for phenindamine

A

Children under 12

18
Q

What are the contraindications for promethazine

A

Comatose states, lower respiratory symptoms (including asthma), pediatric patients less that 2 years of age, subcutaneous or intra-arterial injection

19
Q

Contraindications for hydroxyzine

A

Early pregnancy

20
Q

What are the contraindications for tricyclic dopexins

A

Glaucoma and urinary retention

21
Q

Contraindications for acrivastine

A

Concurrent MAOI therapy, severe coronary artery disease, severe hypertension

22
Q

What is a contraindications for levocabastine

A

Soft contact lens

23
Q

What are contraindications for azelastine

A

Concurrent use of alcohol or other CNS depressants