Pharm Chapter 43- Histamine Flashcards
What drugs are ethanolamines (1st generation)
Diphenhydramine, carbinoxamine, clemastine, dimenhydrinate
What drugs are ethylenediamines (1st generation)
Pyrilamine, tripelennamine
What drugs are alkylamines (first generation)
Chlorpheniramine, brompheniramine
What drugs are piperidines (1st generation)
Cyproheptadine, phenindamine
What drug is a phenothiazine (1st generation)
Promethazine
What drugs are piperazines (1st generation)
Hydroxyzine, cyclizine, meclizine
What drug is a tricyclic dibenzoxepins (1st generation)
Doxepin
What drugs are piperazines (second generation)
Cetirizine
What drug is alkylamine (2nd generation)
Acrivastine
What drugs are second generation piperidines
Loratadine, desloratadine, levocabastine, ebastine, mizolastine, fexofenadine
What drugs are second generation phthalzinones
Azelastine
What are the contraindications for diphenhydramine
Newborns or premature infants, nursing mothers
What are the contraindications for carbinoxamine
Acute asthma attach, MAOI therapy, narrow-angle glaucoma, PUD, severe coronary artery disease, severe hypertension, urinary retention
What are the contraindications for clemastine
Lactation, lower respiratory symptoms, MAOI therapy, newborn/premature infants
What are the contraindications for tripelennamine
Narrow-angle glaucoma, stenosing peptic ulcer, symptomatic prostatic hypertrophy, bladder neck obstruction, pyloroduodenal obstruction, lower respiratory tract symptoms, premature infants, neonates, nursing mothers, concomitant therapy with MAO inhibits
What are the contraindications for brompheniramine
Concurrent MAOI therapy, focal CNS lesions
What are the contraindications for phenindamine
Children under 12
What are the contraindications for promethazine
Comatose states, lower respiratory symptoms (including asthma), pediatric patients less that 2 years of age, subcutaneous or intra-arterial injection
Contraindications for hydroxyzine
Early pregnancy
What are the contraindications for tricyclic dopexins
Glaucoma and urinary retention
Contraindications for acrivastine
Concurrent MAOI therapy, severe coronary artery disease, severe hypertension
What is a contraindications for levocabastine
Soft contact lens
What are contraindications for azelastine
Concurrent use of alcohol or other CNS depressants