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CP Final > Pharm > Flashcards

Pharm Flashcards

1
Q

What is the major NT of the parasympathetic? What are its exceptions

A

ACh; it innervates adrenal medulla directly and also affects sweat glands

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2
Q

What is the precursor to epi and NE

A

Tyrosine->dopa->dopamine

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3
Q

Where is tyrosine converted to dopa and dopamine

A

Nerve cytoplasm

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4
Q

Where does dopamine -> NE -> epi

A

Within vessicles

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5
Q

What synthesizes ACh

A

ChAT

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6
Q

What inhibits ACh from being put in vessicles

A

Vesamicol through the ACh Co-T

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7
Q

What affects ACh release

A

VAMPS and SNAPS

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8
Q

What affects ACh destruction

A

Acetylcholinesterase on the effector cell membrane

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9
Q

What does botulinum toxin interact with

A

ACh release

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10
Q

What blocks reuptake of NE

A

Cocaine by way of NET (NE transporter)

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11
Q

What moves NE, Epi, DA, and serotonin into vesicles

A

VMAT2

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12
Q

What signaling method is used by all adrenergic receptors

A

GPCR

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13
Q

SM of blood vessels (IS/IS NOT) innervated by parasympathetic neruons

A

IS NOT

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14
Q

What must be intact for parasympathetic release of ACh to relax vessels

A

Endothelium

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15
Q

What breaks down catecholamines in cells

A

MAO and COMT

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16
Q

What is β2 function

A
  • Vasodilation
  • Slightly decreased peripheral resistance
  • bronchodilation
  • increased muscle and liver glycogenesis
  • increased release of glucagon
  • relaxed uterine SM
17
Q

What is α1 function

A
  • vasoconstriction
  • increased peripheral resistance
  • increased BP
  • mydriasis
  • increased closure of bladder sphincter
18
Q

What is β1 function

A
  • tachycardia
  • increased lipolysis
  • increased myocardial contractility
  • increased release of renin
19
Q

What receptors do somatic neurons use

A

Nicotinic ACh

20
Q

What are not found on SM of blood vessels

A

mAChR or nAChR

CP Final (14 decks)

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