Pharm Flashcards
1
Q
Ezetimibe
A
Decreased intestinal absorption of cholesterol
Liver increases LDL receptor expression, which draws cholesterol out of the circulation
2
Q
Dobutamine
A
Beta adrenergic agonist with activity on B1 receptors. Causes Gs protein GTP binding , leading to increased production of cAMP. Increased cAMP causes calcium channel activation and increased cystolic Ca concentration. Positive ionotrope and positive chronotrope. Also causes vasodilation