Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Infectious Disease 2 > Pharm 28 > Flashcards

Pharm 28 Flashcards

1
Q

What are the class ASEs of azole derivatives?

A

Increases LFT’s
Prolongs QTc
Inhibits CYP3A4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the available formulations of Clotrimazole?

A

Topical

Oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What are the specific indications of Clotrimazole?

A

Candidia (cutaneous/oropharyngeal/vulvovaginal)

Tineas (unguium/pedis/corporis/capitis)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the available formulations of Fluconazole?

A

Oral

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the specific indications of Fluconazole?

A

Meningitis

Valley fever

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are the additional ASEs of Fluconazole?

A

Inhibits CYP2C9

Inhibits CYP2C19

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are the available formulations of Voriconzaole?

A

Oral

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the specific indications of Voriconazole?

A

Aspergillosis

Non-albicans invasive candida

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the additional ASEs of Voriconazole?

A

Visual changes

Hepatotoxicity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are the available formulations of Posaconazole?

A

Oral

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the specific indications of Posaconazole?

A

Mucormycosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the additional ASEs of Posaconazole?

A

Thrombophlebitis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the available formulations of Itraconazole?

A

Oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the available formulations of Isavuconazonium?

A

Oral

IV

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is the ending common to all drugs in the echinocandins class?

A

“-fungin”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the available formulations of all drugs in the echinocandins class?

A

Parenteral only

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What are the specific indications of all drugs in the echinocandins class?

A

Invasive candida

Invasive aspergillosis

18
Q

What are the available formulations of Amphotericin B?

A 
Oral
IV 
IM/SubQ
Aerosolization
Intraperitoneal
Intravitreal
Intrathecal
19
Q

What are the specific indications of Amphotericin B?

A

Yeast refractory to tx

Mold refractory to tx

20
Q

What are the ASEs of Amphotericin B?

A 
Nephrotoxicity
Hepatotoxicity
Electrolyte abnormalities (K, Na, Mg)
Arrhythmias 
Pancytopenia
21
Q

What are the benefits to using lipid formulations of Amphotericin B (Amphotericin B Lipid complex/Lipidosomal Amphotericin B)?

A

Less nephrotoxicity

22
Q

What are the available formulations of Nystatin?

A

Topical

Oral

23
Q

What are the specific indications of Nystatin?

A

Candida

24
Q

What are the available formulations of Terbinafine?

A

Topical

Oral

25
Q

What are the specific indications of Terbinafine?

A

Onychomycosis (systemic)

26
Q

What are the ASEs of Terbinafine?

A

Inhibits CYP2D6

27
Q

What are the available formulations of Tolnaftate?

A

Topical

28
Q

What are the specific indications of Tolnaftate?

A

Fungi

29
Q

What are the available formulations of Ciclopirox?

A

Topical

Laquer

30
Q

What are the specific indications of Ciclopirox?

A

Onychomycosis

31
Q

What are the available formulations of Griseofluvin?

A

Oral

32
Q

What are the specific indications of Girseofluvin?

A

Tinea capitis

33
Q

What population is Griseofluvin CI in?

A

Pregnant women

34
Q

What are the available formulations of Flucytosine?

A

Oral

IV

35
Q

What are the specific indications of Flucytosine?

A

Combination therapy with Amphotericin B or Fluconazole

36
Q

What is the first line treatment of aspergillosis?

A

Voriconazole

37
Q

What is the alternative treatment of aspergillosis?

A

Amphotericin B

38
Q

What is the salvage treatment of aspergillosis?

A

Echinocandins (capsofungin >micafungin)
OR
Posaconazole

39
Q

What is the first line treatment of candida?

A

Nystatin

40
Q

What is the alternative treatment of candida?

A

Fluconazole
Echinocandin
Amphotericin B lipid complex

41
Q

What two antifungal drugs require renal dosing?

A

Fluconazole

Flucytosine

Infectious Disease 2 (6 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions