Parasites Flashcards
Malaria (aka blackwater fever) causative organism?
Plasmodium Falciparum
How is Malaria transmitted?
Bite of infected female Anopheles mosquito
What is the MC geographic distribution of Malaria?
Tropical and subtropical regions
Diagnostic testing for Malaria?
Thick and thin smears
Ribax - rapid detection
What are some physical features that indicate poor prognosis in pts with Malaria?
Agitation Hyperventilation Hypothermia Bleeding (nose, rectal, etc.) Deep coma Anuria Shock
What medication do you take if you were going to go on a medical mission to Haiti?
Chloroquine phosphate OR hydroxychloroquine
What medication do you give when a pt will be traveling for a longer duration (ie. religious missions)?
AND who is it contraindicated in?
Mefloquine
- pts with seizures and psych conditions
What should you warn pts about when taking Doxycycline?
Photosensitivity and GI side effects
What two medication regimens makeup Malarone?
Atovaquine + Proguanil
- $$$
What drugs are used for uncomplicated Malaria?
Artemether + Lumefantrine
What can primaquine cause?
Hemolytic anemia in G6PD deficiency
Severe malaria should be managed with what?
IV Artesunate
What is the causative organism of Schistosomiasis?
Schistosoma (AKA snail fever)
How is Schistosomiasis transmitted?
Blood flukes entering skin from contaminated water (walking barefoot on a beach)
What species does Katayama fever occur primarily in?
S. Mansoni and S. Japonicum species
S/Sx of Katayama fever?
Chest pain
Hematochezia
Hepatosplenomegaly
What will you find in diagnostic testing for Schistosomiasis?
Eosinophilia
Excreted eggs in stool and urine sample
What is the management of Schistosomiasis?
Praziquantel
Causative Organism of Toxoplasmosis?
Toxoplasma gondii
How is Toxoplasmosis transmitted?
Inhalation of oocyst from cat feces
Ingestion of oocysts in raw pork
Vertical transmission from mom to fetus (highest risk 3rd trimester)
What is the biggest concern with congenital infection from toxoplasmosis?
Retinochoroditis
- MC late finding
What is the diagnostic testing for Toxoplasmosis and what do you see?
CT or MRI: ring-enhancing lesions
What is the tx for Toxoplasmosis?
Pyrimethamine and sulfadiazine w/leucovorin
What is the causative organism of Scabies (AKA 7 yr itch)?
Sarcoptes scabiei —> linear burrows
What is the treatment for scabies?
Permethrin 5%
Ivermectin
Lindane 1% (don’t use in peds)
- + antihistamine