Parasites Flashcards
Malaria (aka blackwater fever) causative organism?
Plasmodium Falciparum
How is Malaria transmitted?
Bite of infected female Anopheles mosquito
What is the MC geographic distribution of Malaria?
Tropical and subtropical regions
Diagnostic testing for Malaria?
Thick and thin smears
Ribax - rapid detection
What are some physical features that indicate poor prognosis in pts with Malaria?
Agitation Hyperventilation Hypothermia Bleeding (nose, rectal, etc.) Deep coma Anuria Shock
What medication do you take if you were going to go on a medical mission to Haiti?
Chloroquine phosphate OR hydroxychloroquine
What medication do you give when a pt will be traveling for a longer duration (ie. religious missions)?
AND who is it contraindicated in?
Mefloquine
- pts with seizures and psych conditions
What should you warn pts about when taking Doxycycline?
Photosensitivity and GI side effects
What two medication regimens makeup Malarone?
Atovaquine + Proguanil
- $$$
What drugs are used for uncomplicated Malaria?
Artemether + Lumefantrine
What can primaquine cause?
Hemolytic anemia in G6PD deficiency
Severe malaria should be managed with what?
IV Artesunate
What is the causative organism of Schistosomiasis?
Schistosoma (AKA snail fever)
How is Schistosomiasis transmitted?
Blood flukes entering skin from contaminated water (walking barefoot on a beach)
What species does Katayama fever occur primarily in?
S. Mansoni and S. Japonicum species
S/Sx of Katayama fever?
Chest pain
Hematochezia
Hepatosplenomegaly
What will you find in diagnostic testing for Schistosomiasis?
Eosinophilia
Excreted eggs in stool and urine sample
What is the management of Schistosomiasis?
Praziquantel
Causative Organism of Toxoplasmosis?
Toxoplasma gondii
How is Toxoplasmosis transmitted?
Inhalation of oocyst from cat feces
Ingestion of oocysts in raw pork
Vertical transmission from mom to fetus (highest risk 3rd trimester)
What is the biggest concern with congenital infection from toxoplasmosis?
Retinochoroditis
- MC late finding
What is the diagnostic testing for Toxoplasmosis and what do you see?
CT or MRI: ring-enhancing lesions
What is the tx for Toxoplasmosis?
Pyrimethamine and sulfadiazine w/leucovorin
What is the causative organism of Scabies (AKA 7 yr itch)?
Sarcoptes scabiei —> linear burrows
What is the treatment for scabies?
Permethrin 5%
Ivermectin
Lindane 1% (don’t use in peds)
- + antihistamine
What is the causative organism of Pediculosis?
Pediculus humanus capitus and corporis
Body lice can also transmit or carry what?
Rickettsia prowazekii - causative agent for epidemic typhus
What is treatment for Pediculosis?
Permethrin (RID, Nix) - tx of choice
Ivermectin (Sklice)
What is the causative organism of bedbugs?
Cimex Lectularis (MC bedbug in US)
What is the transmission of bedbugs?
Fomite contact
mattresses, cushions, pillows, crevices of wooden beds
What is the MC sx if bitten by bedbugs?
ITCHINGGGG
What is the tx for bedbugs?
Malathion
Lindane
Calamine lotion
What is the causative organism of Ascariasis?
Ascaris Lumbricoides
How is Ascariasis transmitted?
Fecal-oral route
- eggs in warm moist contaminated soil
What is Loeffler’s syndrome?
Eosinophilic pneumonia
- Caused by Ascariasis
What are the diagnostic testing for Ascariasis?
Eosinophilia
Stool samples x 3 to identify eggs
What is tx for Ascariasis?
Mebendazole
Albendazole
Ivermectin
How do you prevent Ascariasis?
Sanitation and proper hygiene
What is the causative organism of Enteroviasis?
AKA pinworms
Enterobius vermicularis
How is Enteroviasis transmitted?
Ingestion of eggs from perianal area of infected individuals
What age group is Enteroviasis MC in?
Children 5-10 yrs old
MC sx from a pt infected Enteroviasis?
pruritus ani
Where do the male and female make in a pt infected with Enteroviasis?
Terminal ileocecal region
Diagnostic testing for Enteroviasis?
Scotch tape test
What is the management of Enteroviasis?
Albendazole
Mebendazole
Pyrantel Pamoate
What is the causative organism of Necatoriasis?
AKA Hookworm
Necator Americanus
How is Necatoriasis transmitted?
Dermal exposure to fecal contaminated soil
MC cause from Necatoriasis?
Iron deficiency anemia
Diagnostic testing for Necatoriasis?
Serial stool samples (O&P) - most diagnositic
Eosinophilia
Microcyotic Anemia
What is the management of Necatoriasis?
Mebendazole
Albendazole
Pyrantel Pamoare
Iron supplement
What is the causative organism of Cysticercosis/Pork Tapeworm?
Taenia solium
How is Cysticercosis/Pork Tapeworm transmitted?
Ingestion of infected measly pork containing cysticerci
A clinical manifestation: Cysticericosis from Cysticercosis/Pork Tapeworm can cause what?
Asymptomatic until cust degrade which actives the immune system
- may migrate to brain, eyes, and/or striated muscle
A clinical manifestation: Neurocysticerosis from Cysticercosis/Pork Tapeworm can cause what?
Seizure (MC), altered mental status
What is the management of Cysticercosis/Pork Tapeworm and management for beef tapeworm?
Praziquantel
What is the causative organism of beef tapeworm?
Taenia Saginata
How is beef tapeworm transmitted?
Ingestion of infected “measly: beef containing cysticerci
What is the causative organism of Trichinellosis/Trichinosis?
Trichinella spiralis
How is Trichinellosis/Trichinosis transmitted?
Ingestion of encysted larvae in undercooked pork or bear meat
What is the MCC of death in a pt who has been infected with Trichinellosis/Trichinosis?
Myocarditis
What are S/Sx of someone who has been infected with Trichinellosis/Trichinosis?
Muscle pain and swelling
Weakness
Periorbital edema
Splinter hemorrhages
What is diagnostic for Trichinellosis/Trichinosis?
Muscle biopsy
What is the treatment for Trichinellosis/Trichinosis?
Mebendazole
Albendazole
Prednisone