PHARM

Question 1

Enzyme Inducers?

Answer 1

PC BRASSS

Phenytoin
Carbamazepine
Barbiturates
Rifampicin
Alcohol [Chronic]
Sulfonylureas [Gliclazide]
Smoking
St John’s Wort

Question 2

Enzyme Inhibitors?

Answer 2

OAAK DEVICES

Omeprazole
Amioderone
Allopurinol
Ketoconazole
Disulfiram
Ethanol [Acute]
Valproate
Isoniazid
Ciprofloxacin
Erythromycin
Sulphonamides

Question 3

Drugs Causing Pulmonary Fibrosis?

Answer 3

NE SCARS

Nitrofurantoin
Ergot DA R Agonists
Sulfasalazine
Cytotoxic [Bleomycin]
Amioderone
Rheumatoid [Methotrexate]

Question 4

Screening Pre Starting Azathioprine?

Answer 4

TPMT Enzyme Deficiency

Question 5

Screening Pre Starting Allopurional [High Risk = Afro Caribbean / Asian]?

Answer 5

HLA-B*5801

Question 6

Drugs Causing Agranulocytosis?

Answer 6

5C

Carbamazapine
Carbimazole
Co-Trimoxazole
Clozapine
Cytotoxic [Methotrexate]

Question 7

Beta Blocker Side Effects?

Answer 7

OH BETA

Orthostatic Hypotension
Bronchospasm
Erectile Dysfunction
Trouble Sleeping
Arrhythmias

Question 8

Drugs Causing Urinary Retention?

Answer 8

ADD ON

Amitriptyline [Tri Cyclic Anti Depressants]
Anticholinergics
Disopyramide

Opioids
NSAIDs

Question 9

Drugs Causing Urticaria?

Answer 9

ACE Inhibitors
Aspirin
NSAIDs

Question 10

Overdose + Dilated Pupils + Dry Mouth + Seizures + ECG = Long QTc?

Answer 10

Tricyclic Antidepressant OD [Amitriptyline]

Management
1) IV Sodium Bicarbonate

Question 11

Beta Blocker Overdose Management?

Answer 11

Glucagon