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MSRA 25 > HAEM > Flashcards

HAEM Flashcards

1
Q

B12 / Folate Deficiency Blood Film?

A

Hypersegmented Neutrophils

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2
Q

B12 Deficiency Investigation?

A

Serum Anti Intrinsic Factor Antibodies

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3
Q

Von Willebrand Diagnostic Test?

A

PFA 100

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4
Q

Factor V Leiden Pathophysiology?

A

Activated Protein C Resistance

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5
Q

Initial Anticoagulation for PE / DVT?

A

Apixaban / Rivaroxaban

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6
Q

Vincristine Complication?

A

Peripheral Neuropathy

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7
Q

Doxorubicin Complication?

A

Cardiac Toxicity

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8
Q

Bleomycin Complication?

A

Pulmonary Fibrosis

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9
Q

Cyclophosphamide Complication?

A

Haemorrhagic Cystitis

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10
Q

Co-Prescription with Cyclophosphamide?

A

MESNA

[Sodium 2 Mercaptoethanesulfonate]

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11
Q

Blood Film = Auer Rods?

A

Acutely Myeloblastic Leukaemia

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12
Q

T(9;22) Philadelphia Chromosome Diagnostic?

A

Chronic Myeloid Leukaemia

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13
Q

CML Management?

A

Imatinib

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14
Q

Blood Film = Smudge Cells?

A

Chronic Lymphoblastic Leukaemia

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15
Q

Blood Film = Reed Sternberg Cells [Owl Eyes]?

A

Hodgkins Lymphoma

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16
Q

Amyloidosis Diagnosis?

A

Biopsy + Congo Red Staining

17
Q

Hereditary Haemochromatosis 1st Line Management?

A

Venesection

[TSAT < 50%]

18
Q

Blood Film = Tear Drop Poikilocytes?

A

Myelofibrosis

19
Q

Darriers Sign [Induced Wheal Reaction]?

A

Systemic Mastocytosis

20
Q

Microcytic + Hypochromic Anaemia?

A

Iron Deficiency Anaemia

Management
1) Treat Cause
2) PO Iron

21
Q

Macrocytic Anaemia + Swollen Tounge + Peripheral Neuropathy?

A

B12 / Folate Deficiency

22
Q

B12 Deficiency Investigation?

A

Anti Intrinsic Factor Antibody

23
Q

B12 Deficiency Management?

A

IM Hydroxocobalamin

24
Q

Most Common Bleeding Disorder?

A

Von Willebrands Disease

25
Q

Most Common Clotting Disorder?

A

Factor V Leiden

26
Q

Chemotherapy Common Side Effects?

A

ChemoTox Man

Decradon = Puffy Face
Bleomycin = Pulm Fibrosis
Cisplatin = Ototoxic / Neophrotoxic
Doxorubicin = Cardiomyopathy
Cyclophosphamide = Haemorrhagic Cystitis
Vincristine = Peripheral Neuropathy

27
Q

Back Pain + High Calcium + Anaemia?

A

Multiple Myeloma

AI CRAB

Amyloidosis / Infection / Calcium / Renal / Anaemia / Bone Pain

MSRA 25 (18 decks)

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