ENDO Flashcards

1
Q

Tanned + HypoNatraemia + HyperKalaemia?

A

Addisons Disease
[Low Aldosterone]

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2
Q

HTN + HyperNatraemia + HypoKalaemia?

A

Bilateral Adrenal Hyperplasia
[High Aldosterone]

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3
Q

Cushings Syndrome 1st Line Investigation?

A

Overnight Dexamethasone Suppression Test

Low Cortisol = Cushings Disease
High Cortisol = Ectopic ACTH [Small Cell Lung Cancer]

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4
Q

Hyperaldosteronism 1st Line Investigation?

A

Plasma Aldosterone:Renin Ratio

High Renin = Bilateral Adrenal Hyperplasia
Low Renin = Renal Artery Stenosis

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5
Q

Addisons Disease 1st Line Investigation?

A

Short SynACTHen Test

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6
Q

Phaechromocytoma 1st Line Investigation?

A

24Hr Urinary Metanephrine + Catecholamines

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7
Q

Diabetes Insipidus 1st Line Investigation?

A

Fluid Deprivation Test

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8
Q

MEN1 Features?

A

3P
Hyperparathyroidism
Pituitary Tumour
Pancreatic Tumour

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9
Q

MEN 2A Features?

A

2P + 1M
Hyperparathyroidism
Phaeochromocytoma
Medullary Thyroid Cancer

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10
Q

MEN2B Features?

A

1P + 2M
Phaeochromocytoma
Medullary Thyroid Cancer
Marfans / Mucosal Neuroma

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11
Q

Carcinoid Syndrome 1st Line Investigation?

A

Urinary 5-HIAA

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12
Q

Hyperthyroidism Management in Pregnancy?

A

1st T = Propylthiouracil
2nd/3rd T = Carbimazole

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13
Q

Acromegaly Gold Standard Investigation?

A

Oral Glucose Tolerance Test

[Screening = IGF-1 Levels]

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14
Q

T2DM Management?

A

Medical Mx IF HbA1c >48 [Despite Lifestyle Changes]

1) Metformin
2) Add SGLT-2 Inhibitor [Dapaglifozin] IF HF/CVD

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15
Q

Most Common Cause of Hyperthyroidism?

A

Graves Disease

Investigation
1) Anti TSH + IgG Autoantibodies

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16
Q

Hyperthyroidism + Recent Viral Illness + Painful Goitre?

A

De Quervain’s Thyroiditis

17
Q

Hyperthyroidism + Patchy Uptake on Scintigraphy?

A

Toxic Multinodular Goitre

18
Q

Hypotension + Hypoglycaemia + Abdo Pain?

A

Addisonian Crisis

Management
1) IV Hydrocortisone

19
Q

HTN + Hyperglycaemia + Weight Gain + Muscle Weakness?

A

Cushing Syndrome

20
Q

HTN + Diabetes + Spade Hands?

A

Acromegaly
[Growth Hormone Secreting Pituitary Adenoma]

21
Q

Hyperthyroidism + Well Defined Uptake on Scintigraphy?

A

Toxic Multinodular Goitre

22
Q

Addisons Disease Management?

A

1) Hydrocortisone [Glucocorticoid] + Fludrocortisone [Mineralocorticoid]