ENDO Flashcards
Tanned + HypoNatraemia + HyperKalaemia?
Addisons Disease
[Low Aldosterone]
HTN + HyperNatraemia + HypoKalaemia?
Bilateral Adrenal Hyperplasia
[High Aldosterone]
Cushings Syndrome 1st Line Investigation?
Overnight Dexamethasone Suppression Test
Low Cortisol = Cushings Disease
High Cortisol = Ectopic ACTH [Small Cell Lung Cancer]
Hyperaldosteronism 1st Line Investigation?
Plasma Aldosterone:Renin Ratio
High Renin = Bilateral Adrenal Hyperplasia
Low Renin = Renal Artery Stenosis
Addisons Disease 1st Line Investigation?
Short SynACTHen Test
Phaechromocytoma 1st Line Investigation?
24Hr Urinary Metanephrine + Catecholamines
Diabetes Insipidus 1st Line Investigation?
Fluid Deprivation Test
MEN1 Features?
3P
Hyperparathyroidism
Pituitary Tumour
Pancreatic Tumour
MEN 2A Features?
2P + 1M
Hyperparathyroidism
Phaeochromocytoma
Medullary Thyroid Cancer
MEN2B Features?
1P + 2M
Phaeochromocytoma
Medullary Thyroid Cancer
Marfans / Mucosal Neuroma
Carcinoid Syndrome 1st Line Investigation?
Urinary 5-HIAA
Hyperthyroidism Management in Pregnancy?
1st T = Propylthiouracil
2nd/3rd T = Carbimazole
Acromegaly Gold Standard Investigation?
Oral Glucose Tolerance Test
[Screening = IGF-1 Levels]
T2DM Management?
Medical Mx IF HbA1c >48 [Despite Lifestyle Changes]
1) Metformin
2) Add SGLT-2 Inhibitor [Dapaglifozin] IF HF/CVD
Most Common Cause of Hyperthyroidism?
Graves Disease
Investigation
1) Anti TSH + IgG Autoantibodies