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Block 7 > Pharm > Flashcards

Pharm Flashcards

1
Q

Tafenoquine

A

No hypnosoite, erythrocyte, gametocytes; ppx falci. Hemolytic anemia. No G6PD defic, preg, metformin, platinum

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2
Q

AE & tx MTX vs 5FU

A

Aloepecia, pulm fib/restrictive lung dz, ab, hepato/nephrotox, folate defic/megalo anemia, mucositis, leuvocortin to counter; tx ectopic/molar, RA, psoriasis, immunosuppression vs diarrhea, photosensitive/hyperpig, mucositis, leuvocortin to counter; tx solid tumors

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3
Q

DI aza vs mofetil

A

Cyclosporine, TMP/SMX, mofetil vs cyclosporine, aza, PPI, antacids, contraception

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4
Q

Emetogenics (3). Hẻm vs solid vs hem+solid

A

Cyclophosphamide, carmustine, cisplatin. Cytrabine vs 5FU, platin vs phosphamides, gemcit, oxaliplatin

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5
Q

Bort vs Abe vs nira-ib

A

MM, no 26S proteasome vs no CDK4/6, HER2 neg brca vs inc PARP, br/ov/fallopian tube ca

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6
Q

Immunomod thalidomide vs viral talimogene

A

No cell growth/angiogen, inc T cell cytok; MM, 1o brain vs inc GM-CSF for anti tumor; melanoma

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7
Q

AE ritux vs cetux vs beva. ADC: gem-mab vs ibru-mab

A

Serum sick, PML vs acne, rare serum sick vs hem/thrombotic. DsDNA breaks & antiCD33 for AML; tumor lysis, hepatotox fatal vs apop & antiCD20 w/ ritux for NHL; myelosuppression, rash

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8
Q

Integrate inhib: ralte vs elvite vs dolute vs Cabot. Ibalizumab. AE for both categories

A

Rhabdo, HS; vs w/ food; vs genetic barrier resistance vs PrEP. Block HIV entry, prevent cell to cell fusion. Hep tox, elev glu vs not for naive pts, IV infusion q2wks, IRIS

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9
Q

AE maravoc vs enfurvitide vs ibalizumab. DI protease inhib

A

Transaminitis rash, hep tox vs injxn site rxn, PNA vs IRIS. CYP450 inhib, statins, glucocorticoid, PDE5 inhib, topical lidocaine

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10
Q

HIV meds w drug interactions: rilpivirine vs atazanavir vs integrase inhib

A

Acid suppression vs same vs poly valent cations

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11
Q

CI quinine. AE F stim vs Sag stim vs oprelvelkin

A

MG, optic neuritis, G6PD defic, prolong QTc. Bone/pain vs chest/bone pain, myalgia, rigor, capillary leak vs fluid rtn/edema, cardiomegaly

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Block 7 (17 decks)

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