Pharm

Question 1

contraindications to heparin use?

Answer 1

• hemorhage
• hemophilia
• active gastroduodenal ulcer
• thrombocytopenia
• allergy
• recent major trauma
• hemorhagic CVA

Question 2

MOA of LMWH

Answer 2

inactives factor Xa

Question 3

LMWH will accumulate in ______

Answer 3

renal failure

Question 4

enoxaparin AKA

Answer 4

clexane

Question 5

prophylactic dose of enoxaparin?

Answer 5

40 mg SC OD

Question 6

Innohep =

Answer 6

tinzaparin

Question 7

unfractionated heparin MOA

Answer 7

binds antithrombin and inhibits thrombin, factor Xa and IXa

Question 8

uses of unfractionated heparin?

Answer 8

• anticoagulation for prosthetic heart valves

- acute limb ischemia

Question 9

dose and monitoring of heparin?

Answer 9

• stat 5000 IU bolus
• 1000 IU / hour
• check aptt 4- 6 hrs and aim for apt of 60-90

Question 10

warfarin MOA

Answer 10

inhibits vitamin K dependent clotting factors

Question 11

how to reverse warfarin?

Answer 11

• Vitamin K
• Prothrombin concentrate complex
• fresh frozen plasma

Question 12

advantages of NOACs

Answer 12

• no need for INR monitoring
• no bridging
• short half life - out of system in 24-75 hours

Question 13

aspirin MOA

Answer 13

• cyclooxegenase inhibitor

- inhibits platelet aggregatin

Question 14

whats is the dose for low dose aspirin?

Answer 14

75 mg

Question 15

what is the dose for high dose aspirin?

Answer 15

300 mg

Question 16

plavix AKA

Answer 16

clopidegrel

Question 17

MOA of clopidegrel

Answer 17

ADP receptor antagonist, block platelet aggregation

Question 18

what is the WHO pain ladder?

Answer 18

• single analgesics
• weak opioids
• strong opioids

Question 19

paracetomol drug name

Answer 19

acetominophen

Question 20

metabolism of paracetomol?

Answer 20

hepatic

Question 21

NSAIDs

Answer 21

inhibit COX1 and COX2

-analgesic and antiinflammatory effect

Question 22

what are the weak opioids?

Answer 22

tramadol

codeine

Question 23

side effects of opioids?

Answer 23

-constipation, nausea/vomiting, hypotension, drowsiness, toxicity, dependence

Question 24

what should you prescribe with opioids?

Answer 24

laxative and antiemetic

Question 25

strong opioids?

Answer 25

morphine
oxycontin
oxynorm
oramorph

Question 26

antibiotics for community aquired LRTI?

Answer 26

co-amoxiclav

IF ALLERGIC - levofloxacin

Question 27

antibiotics for hospital aquired LRTI?

Answer 27

tazobacin

IF ALLERGIC - clindamycin/vancomycin/metronidazole

Question 28

abs for urosepsis?

Answer 28

co-amoxiclav & gentamicin

Question 29

treatment for cellulitis?

Answer 29

flucloxacillin

Question 30

SE of statins?

Answer 30

muscles aches, abdo discomfort, transaminases, myositis

Question 31

spiriva AKA

Answer 31

tiotropium

Question 32

what is tiotropium?

Answer 32

long acting anticholinergic

Question 33

ventolin =

Answer 33

salbutamol