endocrine medicine Flashcards
hba1c that indiccate diabetes?
> 48 mmol/L
environmental risk factors for TYPE I DM
- viral infections - resp or enterovirus
- higher SES
- Obesity
- Vit D deficiency
- Maternal age, history of preeclampsia in mom, neonatal jaundice
fasting glucose > __ on more than one occasion indicates diabetes
7
random glucose > __ in a patient with hyperglycemia symtpoms indicates diabetes
11.1
plasma glucose > ___ 2 hours after 75 g glucose challenge indicate diabetes
11.1
criteria that indicates DKA
Glucose > 12 mmol/L
Ketones > 3 mmol/L
which antibodies are associated with TYPE I diabetes?
- anti-GAD
- anti islet cell
management of DKA?
- IV infusion of short acting insulin
- aim for reductino of blood glucose of 3 mmol/L per hour and ketones of 0.5 per hour
when treating DKA, if blood glucose falls below ___ you should switch to 5% dextrose
14 mmol/L
how often should you check glucose and ketones in DKA?
hourly
what amount is used for bolus fluid replacements in DKA
1 L/hour initially
hba1c target for glycemic control in diabetes?
<53
BP targets in patients with diabetes?
<140/90, or <130/80 if microvascular disease present