PHAN LAB MID 2 Flashcards
Based on compressing tablets between two jaws
via a spring gauge and screw
Monsanto (Stokes) hardness tester
Vertically mounted tablet was squeezed in a device that resembles a pair of pliers
Pfizer hardness tester
The breaking load was applied through the action of a small hydraulic pump that was first operated
manually but was later motorized.
Strong-Cobb hardness tester
Also known as “Heberlein Tablet ,Hardness
tester.” It is an automated tablet hardness testing
device. Requires electrical power
Schleuniger table hardness tester
LIMITS in TABLET BREAKING FORCE DETERMINATION
Oral tablets: 4 to 10 kg
Hypodermic and chewable: 3 kg
Some sustained release: 10 – 20 kg
Also known as the ”Drop” test or abrasion.
TABLET FRIABILITY TEST
The tablets undergo shock as they fall ___ inches on
each turn.
6 inches
What are the Tablet Processing Problems
Capping and lamination
Picking and sticking
Tablet mottling