Liquid Dosage Forms 1 Flashcards
Refers to a combination of drug substances and excipients to facilitate dosing, administration, and delivery of the medicine to the patient.
DOSAGE FORMS
It relates the drugs activity to its route of
administration.
DOSAGE FORMS
Classification of dosage forms (3)
Route of Administration
Physical Properties
Release Pattern
Tests that are performed to ensure that products in the market are safe and effective at the same time of use and the entire duration of their shelf life.
Product quality tests
Pharmaceutical formulations which
contain a mixture of active drug components dissolved or suspended in a suitable solvent
LIQUID DOSAGE FORMS
Liquid Dosage Forms are ______ and designed to ______________________
Pourable
provide rapid therapeutic effect.
Classifications under ROUTE OF ADMINISTRATION
Topical
By injection
Inhalation
Mucosal
Gastro-intestinal
Classifications under PHYSICAL PROPERTIES
Solid dosage forms
Liquid dosage forms
Semi-solid dosage forms
Classifications under RELEASE PATTERN
Immediate
Delayed
Extended
Liquid dosage forms can be in the form of ____________
Sterile and Non-sterile preparations
General Chapter for Sterility Test
General chapter <71>
General chapter <71> determines?
Determines the presence or absence
of viable organisms
Methods of conducting Sterility Test
Primary - Membrane Filtration
Direst Transfer - Direct Inoculation
the process of removing this microorganisms or germs.
Sterilization
It means free from germs
Sterile
It is a method of choice for pharmaceutical products.
MEMBRANE FILTRATION
Other terms for DIRECT TRANSFER
Direct Inoculation
Test Tube Inoculation Method.
Filter size of membrane filtration
0.45 micrometer
Common media that is primary intended for the culture of anaerobic bacteria as well as aerobic bacteria
Fluid Thioglycolate Medium
Incubation Period for Fluid Thioglycolate Medium
Incubated for 14 days at 30-35 degrees
Celsius
Common media that is primary intended for the culture of both fungi and aerobic bacteria. There is specific role of some ingredients.
Soyabean Casein Digest Medium
Incubation period for Soyabean Casein Digest Medium
Incubated for 14 days at 20-25 degrees
Celsius
Excreted, and can be seen in the cell wall of gram negative bacteria
ENDOTOXIN
Other term for viruses and other
microorganisms that cause diseases.
Pathogens
