Phagocytosis (Non Specific Immunity) - 11/12/23

Question 1

What are some examples of phagocytes? [2]

Answer 1

• Macrophages
• Neutrophils

Question 2

What is a Phagoctye?

Answer 2

A type of WBC that engulf and destroy microorganisms (phagocytosis)

Question 3

Describe the stage of Phagocytosis.

Answer 3

1) Phagocyte is attracted to pathogen (by chemical products of pathogen).
2) It moves towards pathogen along concentration gradient
3) The phagocyte has several receptors on its cell-surface membranes that attach to chemicals on the surface of pathogen
4) Pathogen engulfed
5) Phagosome formed
6) Lysosomes inside phagocyte migrate to phagosome (formed by englufing the bacterium)
7) The lysosomes release lysozymes into phagosome
8) Pathogen is hydrolysed
9) Hydrolysis products of bacterium are absorbed by phagocyte

Question 4

How is phagocyte attracted to pathogen?

Answer 4

By chemical products of pathogen

Question 5

How does phagocyte travel to pathogen?

Answer 5

Along concentration gradient

Question 6

What does WBC do to pathogen at end of phagocytosis?

Answer 6

It’s absorbed by phagocyte

Question 7

What type of immunity is Phagocytosis?

Answer 7

Non-Specific

Question 8

What are 4 Features of a Non-Specific Response?

Answer 8

1. Immediate
2. Same for all pathogens
3. Include physical barriers
4. Includes phagocytosis by phagocytes

Question 9

What is a phagosome?

Answer 9

A vesicle, but with bacterium in the middle

Question 10

What is a lysosome?

Answer 10

A vesicle with lysozymes in the middle

Question 11

What do microorganisms need to get past first to get into body?

Answer 11

Physical and Chemical Barrier