Peutz-Jeghers syndrome

Question 1

What is the inheritance pattern of Peutz-Jaghers syndrome?

Answer 1

Autosomal dominant

Question 2

Name 2 features of PJS

Answer 2

• Hamartomatous polyps
• GI bleeding
• Pigmented lesions on face, lips, oral mucosa, palms and sole of feet
• Small bowel obstruction often is first presenting complaint, often due to intussusception