Petechiae, Purpura, and Vasculitis - Schwarzenberger Flashcards
What is purpura?
Essentially “blood under the skin”
- non-blanchable, pink to purple macules/patches or papules caused by extravasated RBC’s in skin or mucous membranes
3 Main causes of purpura?
- coagulation/clotting abnormalities
- leaky or abnormal blood vessels
- other causes, including trauma
2 types of purpura? Which is associated with inflammation? Inflammatory purpura is a sign for what?
- non-palpable/macular (NON inflammatory)
- palable (inflammatory) = signs of vasculitis
2 types of non-palpable purpura?
petechiae, ecchymosis
What type of non-palpable purpura is this?
Petechiae
Petechiae features?
Size?
Location?
Painful or painless?
- small <3 mm red or purple dots
- usually on dependent areas of body
- generally painless
Who is most likely to have petechiae (2 types of pts)?
pt with hemophilia or with cancer receiving chemotherapy
Petechiae is generally considered to be an abnormality in what?
platelets
Non-platelet related petechiae is usually due to what?
things that increase capillary fragility or allow them to leak
What was the dx of this type of petechiae?
Scurvy, due to vit C defiency
- petechiae associated with hair follicles, hair is curled
Non-scientific name for ecchymosis?
Bruise
Ecchymosis features?
Size?
Location on body?
Painful or painless?
- Larger areas of purpura (>5mm)
- can be anywhere on body
- may/may not be painful, tender
Ecchymosis are usually due to what?
Coagulation defect (hyper or hypocoaguable)
Purpura is multifactorial.
Just know it.
Palpable purpura is a hallmark for ?
Leukocytoclastic vasculitis (this will be on the test. i guarantee it)