Peripheral neuropathy Flashcards
1
Q
What is peripheral neuropathy?
A
Nerve pathology outside CNS, of peripheral nerves
2
Q
What are the mechanisms of peripheral neuropathy?
A
Demyelination
axonal damage
nerve compression
vasa nervorsum infarction
Wallerion degeneration (nerve cut - distally dies)
3
Q
Causes of peripheral neuropathy?
A
Demyelination (Guillain barre, B12 def)
T2DM
Surgery
Pathology eg. infection, endocrine, RA…
4
Q
What is mononeuropathy?
A
Single nerve
5
Q
What is mononeuritis multiplex?
A
Several individual nerves
6
Q
What is polyneuropathy?
A
Diffuse, often symmetrical pathology
7
Q
Mononeuritis multiplex causes?
acronym
A
WARDS PLC
Wegeners
AIDS/amyloidosis
RA
DMT2
Sarcoidosis
Polyarteritis nodosa
Leprosy
Carcinomas
