Brain tumours + 1^ Tumours

Question 1

What is the MC Brain tumour?

Answer 1

Astrocytoma - 90% (type of Glioma)

Question 2

What are the other types of 1^ brain tumours?

Answer 2

Oligodendrocytoma
Meningioma
Schwannoma

Question 3

A glioma is a type of astrocytoma and ?

Answer 3

oligodendrocytoma

Question 4

Astrocytomas are the ? MC paediatric cancer after ?

Answer 4

second
ALL

Question 5

Are 2^ tumours LC or MC than 1^?
What are they?

Answer 5

More common

Metastasis from:
NSCLC (mc) + SCLC
breast, Melanoma, Renal CC, gastric cancer

Question 6

How is it graded?
Severity?
Cure?

Answer 6

Graded 1-4
Grade 2 - 4 = non curative

Question 7

Tx for grade 3/4?

Answer 7

Often metastasised
Chemo/palliative care

Question 8

Do 1^ brain tumours metastasise?

Answer 8

Dont metastasise outside CNS

Question 9

1^ Tumours
Astrocytomas are graded what by who?

Answer 9

1-4 by WHO
1 = benign
4 = Glioblastoma (v bad prognosis, death within a year)

Question 10

1^ tumours
Sx?

Answer 10

High ICP ; Cushings triad (high PP, bradycardia, irregular breathing)
Papillodema (optic disc swells)
CN6 palsy
Focal neurology
Epileptic seizures
Lethargy and weight loss

Question 11

Dx of 1^ tumour?

Answer 11

MRI head - locate tumour then Biopsy - determine grade

Question 12

Why no Lumbar puncture?

Answer 12

High ICP of undetermined cause = massive CI

Question 13

Tx for 1^ tumour?

Answer 13

Surgery (remove tumour if poss and decrease ICP)

Chemo (before/during/after surgery)

Steroids (eg. dexamethasone) may help