Peripheral Nerve Diseases Flashcards
Guillain-Barré Syndrome pathogenesis
usually follows viral illness, inflammatory disease causing demyelination
Guillain-Barré Syndrome description
acute ascending paralysis
Guillain-Barré prognosis
usually resolves via remyelination
Guillain-Barré CSF findings
elevated proteins
no lymphocytes
Type of bacterium causing leprosy
mycobacterium
How does the body kill the leprosy mycobacterium?
forming granulomas
Tuberculoid leprosy
less severe, more localized with good granuloma formation
Lepromatous leprosy
very severe, may lead to autoamputation due to repeated infections and abnormal healing
What viral disease may lead to multinucleated giant macrophage cell?
herpes zoster (or other herpes variants)
Charcot-Marie-Tooth disease: how common?
most common hereditary neurological disease: autosomal dominant (?)
Charcot-Marie-Tooth pathophysiology
repeated demyelination and remyelination
First clinical sign of Charcot-Marie-Tooth
food drop
Charcot-Marie-Tooth: pain and sensory
pain present
sensory not present