Peripheral Nerve Diseases Flashcards

1
Q

Guillain-Barré Syndrome pathogenesis

A

usually follows viral illness, inflammatory disease causing demyelination

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2
Q

Guillain-Barré Syndrome description

A

acute ascending paralysis

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3
Q

Guillain-Barré prognosis

A

usually resolves via remyelination

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4
Q

Guillain-Barré CSF findings

A

elevated proteins

no lymphocytes

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5
Q

Type of bacterium causing leprosy

A

mycobacterium

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6
Q

How does the body kill the leprosy mycobacterium?

A

forming granulomas

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7
Q

Tuberculoid leprosy

A

less severe, more localized with good granuloma formation

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8
Q

Lepromatous leprosy

A

very severe, may lead to autoamputation due to repeated infections and abnormal healing

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9
Q

What viral disease may lead to multinucleated giant macrophage cell?

A

herpes zoster (or other herpes variants)

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10
Q

Charcot-Marie-Tooth disease: how common?

A

most common hereditary neurological disease: autosomal dominant (?)

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11
Q

Charcot-Marie-Tooth pathophysiology

A

repeated demyelination and remyelination

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12
Q

First clinical sign of Charcot-Marie-Tooth

A

food drop

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13
Q

Charcot-Marie-Tooth: pain and sensory

A

pain present

sensory not present

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