CBL 1: Antineoplastics

Question 1

Temazolamide:

• mechanism of action
• cell cycle specificity
• similar drugs

Answer 1

• alkylating agent
• non-specific
• cyclophosphamide

Question 2

Carmustine (nitrosurea)

• mechanism of action
• cell cycle specificity
• similar drugs

Answer 2

• alkylating agent
• non-specific
• cyclophosphamide, temzolamide
• can be used on Gliadel wafer

Question 3

Vincristine

• mechanism of action
• cell cycle specificity
• similar drugs

Answer 3

• inhibits microtubule formation
• M-phase specific
• paclitaxol