Periodontal Considerations Flashcards
During Puberty:
Levels of Prevotella intermedia _____________
Occurs during age _____ to _______
Estrogen/Progesterone levels ______
Gingivitis levels _________________
INCREASE
Age 11 to 14
INCREASE
INCREASE
How to manage puberty gingivitis?
1) OHI (frequent reinforcement)
2) Scaling & polishing
3) Antimicrobial mouth rinses (CHX)
4) Local/systemic antimicrobials if severe & medical history indicates need
During Pregnancy, estrogen levels are _____________, and progesterone levels are ___________
DECREASED (estrogen)
INCREASE (progesterone)
What are the adverse pregnancy outcomes (4) ?
1) Pre-term Birth
2) Low Birth Weight
3) Preeclampsia
4) Fetal Growth Restriction & Development
Menadione is an essential nutrient for ___________
P. intermedia
Menadione =
Methyl-naphthalenedione
Progesterone =
Naphthoquione
P. intermedia can substitute naphthoquione for _____________________
methyl-naphthalenedione.
Elevated progesterone levels will facilitate ________ and _________ of ____________
Growth
colonization
P. intermedia
P. Intermedia is tissue invasive and associated with _______________ and ____________ formation
Gingival inflammation
Pyogenic granuloma formation
What are the inflammatory mediators for pregnancy?
IL1, IL 6 TNF-alpha, and PGE 2
What are the Acute Phase Responses ?
1) C-reactive protein
2) Haptoglobin
3) Fibrinogen
4) Amyloid A
What are the Periodontal pathogens associated with pregnancy?
1) P. gingivalis
2) T. forsythia
3) Campylobacter rectus
4) Provetella intermedia
5) Treponema denticola
* *Endotoxins
Periodontal disease + P. i, Fusobacterium, &
Campylobacter recta —–>
Placental invasion w/ fetal exposure to bacterium, LPS, and bacterial antigens
Periodontal disease can lead to increased levels of ?
1) Inflammatory mediators (IL 1, 6, TNF-a and PGE2)
PGE2 can lead to ____________ contraction
Pre-mature uterine
Premature uterine contraction leads to what?
Pre-term low birth weight delivery
What are the primary objectives for managing periodontal disease in pregnancy ?
1) Achieve a health oral environment
2) Maintain optimal oral hygiene (patient education)
What is the effective Dental Treatment for the 1st Trimester?
No treatment/Emergency only
What is the effective Dental Treatment for the 2nd Trimester?
Safest time frame for treatment
- control active disease
- eliminate potential problems
- postpone periodontal surgery
Last month of 3rd Trimester_________________
Selective treatment
Dental radiographs in Pregnancy?
1) Lead apron
2) High speed film
3) safety established but desirable not to have irradiation during 1st trimester
4) 2008 ADA guidelines: ONLY required to aid in establishing a definitive diagnosis
Medications in Pregnancy?
1) Consult FDA classification system
2) 1-2% of material drug dose is excreted in breast milk
Avoid which drugs during pregnancy?
1) Lidocaine
2) Bupivacaine
3) Procaine
* *Use all these with caution
4) ASPIRIN (AVOID in 3rd trimester)
5) Ibuprofen (AVOID in 3rd trimester)
6) Codeine
7) Oxycodone
8) Hydrocodone
* **AVOID PROLONGED USE
Which ABX should a pregnant woman avoid?
1) Tetracycline **
2) Clarithromycin **
3) Ciprofloxacin
4) Metronidazole
Which drugs to avoid while breast feeding?
1) Aspirin
Which ABX to avoid while breast feeding?
1) Tetracycline **
2) Ciprofloxacin
3) Metronidazole
4) Gentamicin
5) Vancomycin
6) Benzodiazepines
7) Barbiturates
What is considered a medically compromised patient?
1) hypertension
2) Ischemic heart disease
3) congestive heart disease
4) cardiac pacemakers/defibrillators
5) Infectious Endocarditis
6) Ischemic Cerebrovascular disease
Bacteremia leads to what in Atherosclerosis, Cardiovascular & Cerebrovascular disease?
Bacterial induced platelet aggregation & endothelial invasion
Immune response leads to what in Atherosclerosis, Cardiovascular & Cerebrovascular disease?
Antibodies to bacteria and cross-reactive antigens (e.g heat shock protein)
What is the effect of inflammation of the vessel wall in periodontal disease?
Smooth muscle cells + Vascular endothelium–> collagen elastin, Upregulation of ICAM -1 and V CAM-1–> PMNs , macrophages and Foam cells—> Atheroma formation (Coronary vascular disease)
Increased CRP in the liver does what?
Binds to epitopes on lipid membranes of damaged cells leading to CRP– C’ activation leads to PMN chemotatix and phagocyte activation causing tissue damage