Pericarditis Flashcards

1
Q

Pericarditis

A

Inflammatory disorder of the pericardium which involves the visceral or/& parietal pericardial layers

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2
Q

Etiology of pericarditis

A

Infectious
noninfectious
idiopathic

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3
Q

Morphology classification of pericarditis

A

Acute

chronic

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4
Q

Types of acute pericarditis

A

Serous pericarditis

fibrinous /serofibrinous pericarditis

purulent / fibrinopurulent pericarditis

hemorrhagic pericarditis

Caseous/ granulomatous pericarditis

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5
Q

Commonest form of pericarditis

A

Fibrinous/ serofibrinous pericarditis

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6
Q

When do you have serous pericarditis with serous exudate

A

In noninfectious inflammation:

Immunological mediated( rheumatic fever , SLE)

Tumors
uremia
Infection from tissue nearby causing sterile serious effusion

Viral infection
idiopathic

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7
Q

Serous pericarditis morphology

A

Epicardium and pericardium inflammation
few polymorphs ,lymphocytes, macrophages

slow effusion

fibrous adhesions when resolved ( rare)

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8
Q

Fibrinous and serofibrinous pericarditis characteristics

A

Abundant serous effusion with fibrinous exudate

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9
Q

Fibtinous and serofibrinous pericarditis causes

A

Uremia

Acute MI

Autoimmune disease like acute rheumatic fever, SLE, rheumatoid arthritis, post myocardial infraction (Dressler syndrome ) ,chest radiation

post cardiac surgery

trauma

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10
Q

Fibtinous and serofibrinous pericarditis Gross morphology

A

Shaggy granular fibrin deposits the epicardium and pericardium

Yellow and cloudy thick fluid with leukocytes and red cells and fibrin ( serofibrinous pericarditis )

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11
Q

Fibtinous and serofibrinous pericarditis resolution

A

Digestion of the fibrin or organization (fibrous adhesions with partial or complete obliteration of pericardial cavity)

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12
Q

Fibtinous and serofibrinous pericarditis produce what type of sound

A

Rubbing of pericardial surfaces against each other

Loud pericardial friction rub with pain

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13
Q

In what case do you have purulent and fibrinopurulent pericarditis

A

Infection

Mostly bacterial or fungal

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14
Q

Purulent pericarditis Morphology

A

Purulent exudate covers pericardium
Thick creamy pus

Red granular surface

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15
Q

Is complete resolution usual in purulent pericarditis

A

No

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16
Q

Major complication of purulent pericarditis

A

Constrictive pericarditis

17
Q

Most common association to hemorrhagic pericarditis

A

Malignant neoplastic tuberculous involvement of pericardium

18
Q

What often precedes hemorrhagic pericarditis

A

Cardiac surgery

19
Q

Healing of hemorrhagic pericarditis

A

By organization with fibrous adhesions

20
Q

Main cause of caseous/ granulomatous pericarditis

A

Tuberculosis

21
Q

Exudate in caseous pericarditis

A
Acute 
Turbid 
Bloodstained 
Tubercles on pericardial surface 
Subsides with fibrous adhesions

Fibrous tissue enclosing if become chronic
Calcification

22
Q

Type of chronic pericarditis

A

Chronic adhesive pericarditis

Chronic constrictive pericarditis

23
Q

Chronic adhesive pericarditis follows …

A

Pericarditis with fibrinous exudate which organize and form fibrin adhesions

24
Q

Chronic adhesive pericarditis more likely to develop after

A

Purulent pericarditis
Caseous pericarditis
Cardiac surgery
Irradiation

25
What is adhesive mediastinal pericarditis
In chronic adhesive pericarditis there is risk of fibrous adhesions between the parietal pericardium and the Adjacent mediastinal structures
26
Causes of chronic constrictive pericarditis
``` Tuberculosis Purulence Neoplasia Traumatic pericarditis Cardiac surgery Idiopathic Viral pericarditis ```
27
Characteristics of constrictive pericarditis
Pronounced fibrous thickening of pericardium Rigidity of the heart interferes with heart action and circulation ( impaired diastolic relaxation and ventricular filling, decreased cardiac output) Pericardial cavity obliteration Calcification. And hyalinization of pericardium
28
Morphology of heart in constrictive pericarditis
Normal or smaller than normal heart Sometime enlarged