Peptic Ulcer Disease Flashcards
1
Q
What is dyspepsia?
A
Indigestion. It is characterized by:
- Epigastric Pain
- Postprandial Fullness
- Early Satiety
2
Q
Epidemiology of Peptic Ulcer Disease?
A
Very Common Mostly caused by H.pylori infection Increased in NSAID use Smoking Alcohol History of GORD
3
Q
Symptoms?
A
Gnawing Epigastric Pain Vomiting Weight Loss Worse at night (Wakes patient up) Tiredness
4
Q
Describe the pain in Duodenal and Gastric Ulcers?
A
Duodenal Ulcers - Pain relieved on eating
Gastric Ulcers - Pain worse on eating
Duodenal Ulcers - Pain worse 2-3 hours after eating
5
Q
Examination finding in non-perforated Peptic Ulcer?
A
Epigastric Tenderness
6
Q
Examination finding in perforated peptic ulcer?
A
Sudden onset of severe sharp abdominal pain Abdominal Tenderness Rebound Tenderness Guarding Rigidity Signs of Septic Shock
7
Q
Investigations in Peptic Ulcer disease?
A
Stool Test (H.pylori) Urea Breath Test Serum IgG (Against H.pylori) Endoscopy FBC
8
Q
Treatment for peptic ulcer disease?
A
PPIs (Omeprazole)
Antibiotics (Clarithromycin and Metronidazole)
9
Q
Complications of peptic ulcer disease?
A
Perforation (Mainly Duodenal Ulcer)
Haemorrhage
Anaemia
Cancer