Pentose Phosphate Pathway

Question 1

PPP is where ….. is catabolised to form a … and …

Answer 1

glucose-6-phosphate
pentose phosphate
CO2

Question 2

PPP is a critical source of

Answer 2

NADPH and pentose phosphates

Question 3

2 stages of PPP

Answer 3

oxidative stage (3 steps)
non-oxidative stage

Question 4

oxidative steps:
glucose-6-phosphate goes to …. (catalyst and biprods)
This goes to.. (catalyst and biprods)
this goes to… (catalyst and biprods)

Answer 4

6-phosphoglucono-lactone (glucose-6-dehydrogenase + NADH + NAD+)
6-phosphogluconate (lactonase H+)
ribulose-5-phosphate (6-phosphogluconate dehydrogenase NADPH)

Question 5

Non-oxidative steps:
xylulose-5-phosphate goes to… (catalysed by)
this goes to …. (catalysed by)

Answer 5

ribulose-5-phosphate (phosphopentose epimerase)

ribose-5-phosphate (phosphopentose isomerase)

Question 6

from 1 molecule of glucose-6-phosphate, what 2 products are formed

Answer 6

2 NADPH

ribose-5-phosphate

Question 7

glucose-6-phosphate + NADP+ +H20 —->

Answer 7

ribose-5-phosphate +2NADPH +H+ +CO2