Pentose Phosphate Pathway Flashcards
3 pentose phosphates that pentose phosphate pathway synthesizes
Ribulose 5-phosphate
Ribose 5- phosphate
Xylulose 5-phosphate
Oxidative stage
Glucose 6-phosphate -> ribulose 5-phosphate
Non-oxidative stage
If NADPH and nucleotides are needed, ribulose 5-phosphate is converted to ribose 5-phosphate
If NADPH is needed more than ribose 5-phosphate, then pentose phosphates are converted to glycolytic intermediates
of glucose 6-phosphate molecules needed to complete 1 cycle of the pentose phosphate pathway
3 glucose 6-phosphate molecules needed
Isomerases
Convert ribulose 5-phosphate to xylulose 5-phosphate and ribose 5-phosphate
Transketolases
Catalyze transfer of a two-carbon segment from a ketose phosphate to an aldose phosphate
Xylulose 5-phosphate + ribose 5-phosphate -> glyceraldehyde 3-phosphate and a sedoheptulose 7-phosphate (7-carbon compound)
Transaldolases
Catalyze transfer of a 3-carbon segment from a ketose phosphate to an aldose phosphate
Sedoheptulose 7-phosphate + G3P -> erythrose 4-phosphate + fructose 6-phosphate