penile histopath Flashcards
Left: hypospadias—urethral opening on ventral surface of penis; 1/300 live births
Right: Epispadias: abnormal urethral opening on dorsal aspect of shaft; even rarer
Peyronie’s dz: localized fibromatosis of penile shaft resulting in painful erections
Penile Infections:
Left: HSV
Right: Syphillis chancre
Condyloma accuminata (genital warts); due to HPV 6 & 11
Penile carcinoma = SCC; related to HPV infection (serotypes 16 and 18); circumcision is protective; uncommom in USA, more common in Africa & Asia
Tx: surgical removal with adjuvant RT to groin lymph nodes for more advanced lesions
SCC of the penis; well differentiated SCC’s make lots of keratin (PINK); poorly differentiated SCC’s do not; keratin pearls