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1st Year Med School (Random) > Peds Virus Jones > Flashcards

Peds Virus Jones Flashcards

1
Q

CMV symptoms

A

1% have congenital CMV
90% of infected infants are asymptomatic

MC - Microcephaly
Periventricular calcifications
Chorioretinitis
HSM
Purpuric rash - Blue berry rash
Anemia
Thrombocytopenia
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2
Q

CMV Diagnosis

A

Urine can establish dx

CSF, Stool, or respiratory secretions possible

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3
Q

Classic EBV

A 
Fever
Exudative
Adenopathy
HSM
Fatigue for several weeks
Many asymptomatic

Monospot test
Rash w/ amoxicillin/PCN

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4
Q

EBV and Neurologic syndromes

A 
Guillain-Barre syndrome
Aseptic meningitis
Meningoencephalitis
Transverse myelitis
Peripheral neuritis
Facial nerve palsy
Optic neuritis
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5
Q

EBV and hematologic complications

A 
Splenic rupture
Agranulocytosis
Thrombocytopenia
Hemolytic anemia
TTP
DIC
Hemophagocytic lymphohistiocytosis
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6
Q

HSV Transmission, Types, Tx

A

Focus on perinatal infections

SEM
Encephalitis
Disseminated HSV Infections

Tx: IV acyclovir in neonatal period

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7
Q

HSV testing

A

Perform surface viral cultures in newborn 24-36 hrs after delivery

Swab mouth, nasopharynx, conjunctivae, rectum

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8
Q

Varicella-zoster virus

A

Sx: Fever, Malaise, NOT lethargy, anorexia, HA, mild abdominal pain 24-48 hrs prior to rash

Pruritic erythematous macules -> Papules -> fluid filled vesicles

Intermixed stages

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9
Q

Measles Clinical Manifestations

A

Rubeola

High fever
Enanthem (Koplik spots)
Cough, Coryza, Conjunctivitis
Prominent exanthem startingn at head and spreading down the body

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10
Q

Measles Diagnosis

A

Rubeola

Clinical appearance
serology (IgM ab)

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11
Q

Measles Complications

A

Pneumonia
febrile seizures
Encephalitis
Subacute sclerosing panencephalitis (SSPE)

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12
Q

Rubella Congenital syndrome sx

A

Cataracts, Congenital glaucoma, Microphthalmos

Congenital heart disease: PDA or peripheral pulmonary artery stenosis

Hearing Impairment

Neurologic abnormalities: developmental delay, microcephaly

Other: IUGR, interstitial pneumonitis, HSM
“Blueberry muffin” rash, jaundice, thrombocytopenia

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13
Q

Rubella diagnosis

A

IgM antibody

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14
Q

Parvovirus B19 Pathogenesis

A

Viral infections -> possibly postinfectious phenomena (exanthem, arthritis)
Babies in womb and fetal hydrops (2nd trimester)

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15
Q

Parvovirus B19 Clinical manifestations

A

Erythema infectiosum - Slapped cheek rash
Lacy, reticulated rash entire body
transient aplastic crisis rare

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16
Q

Roseola

A

Human Herpesvirus type 6
Hx: Fever for 3 days -> No fever -> christmas tree rash

erythematous maculopapular rash on trunk and extremities
No rash on palms or soles of feet

Other findings: LAD, N/V/D, febrile seizure, respiratory sx

No GI/ sinuses

Tx: Hydration

17
Q

Adenovirus

A

can cause maculopapular rash, will have D, conjunctivitis, or wheezing, constitutional sx

Nasal test

18
Q

HIV

A

Screening tests
younger than 18 months - DNA PCR
If suspected - Nursery -> 14-21 days -> 1-2 months -> 4-6 months

Older than 18 months - Ab test

19
Q

Enteroviruses (echo, coxsackie, entero)

A

Hand-foot-and-mouth disease: Fever, rash from coxsackie
Anterior Oral ulcer, Elliptical vesicles on hands and feet

Herpangina: Fever, sore throat, dysphagia, lesions in Posterior pharynfrom entero

Encephalitis: Neonates - Adolescents
Sick, HA, MILD nuccal rigidity, N/V

20
Q

Influenza Treatment

A

Neuraminidase Inhibitors: for A and B
Oseltamivir 6 months +, liquid
Zanamivir not for wheezers

Influenza A resistance to amantadine and rimantadine

21
Q

RSV

A

MCC of Bronchiolitis

  • MC occurs in children less than 2
    • peak 2-6 mo.

Rapid viral ag test: nasopharyngeal secreations

22
Q

Hep V virus

A

In utero exposure:

HBsAg dx acute HBV

23
Q

Rabies

A

Bats, Raccoons, Skunks bites

Tx: Vacc + Ig 4-5 doses
0 - 1 - 7 - 14 - 28 days

24
Q

Parainfluenza

A

“Croup” stridorous

25
Q

Adenovirus

A

URI with conjunctivitis, D - multisystem

26
Q

Rotavirus

A

Severe, Water Diarrhea

cruises

27
Q

Rhinovirus

A

Common cold

MC in children

28
Q

Arbovirus

A

WNV

Dengue fever

29
Q

Hep A

A

Food handling

Dx: IgM Ab

30
Q

Hep C

A

Check for transmission to baby at 18 months

1st Year Med School (Random) (20 decks)

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