Peds Pharmacology

Question 1

Rocefin sx in children

Answer 1

jaundice

Question 2

Erythromycin SE in children

Answer 2

pyloric stenosis

Question 3

Don’t use Adderall with what ECG rhythm

Answer 3

prolonged QT

Question 4

Ketoconazole SE

Answer 4

ergosterol may cause nausea/ vomitting

Question 5

Ketoconazole not for…

Answer 5

Aspergillosis or cryptococcus or mucormycosis

Question 6

Imipramine

Answer 6

TCA

Question 7

Imipramine overdose

Answer 7

look for QRS widening. Tx with bicarb for acidemia

Question 8

Ampho B

Answer 8

Amphotericin B is active against a broad array of fungi, including Candida, Aspergillus,
Zygomycetes, Histoplasma, and Coccoides immitis.

Beware hypokalemia and nephrotoxicity

Liposomal preparations of amphotericin are equally
efficacious and less nephrotoxic than the standard product

Question 9

Opiate withdrawal syndrome

Answer 9

keep newborn for 5 days

Question 10

side effect of hydroxyurea

Answer 10

neutropenia/ thromobocytopenia/ anemia

Question 11

absence seizure tx

Answer 11

1. Ethosuximide

2. Valproate

Question 12

Partial Seizures

Answer 12

1. Phenytoin

2. Gabapentin

Question 13

TCA overdose tx

Answer 13

Sodium Bicarb

Question 14

Recreational drug that causes IUGR

Answer 14

methadone (opiates)

Question 15

Valproic acid effect on fetus

Answer 15

neural tube defects,
cleft lip or dysmorphic face

broad nasal bridge
long philtrum

Question 16

phenytoin (hydantoin syndrome)

Answer 16

nail/digit hypoplasia

Question 17

FAS

Answer 17

smooth philtrum
small palpebral fissures
thin upper lip

Question 18

Hyperactive Moro reflex caused by what

Answer 18

cocaine

Question 19

abstinence from opiates causes

Answer 19

high-pitched cry,
tremors/seizures
sneezing

tachypnea
vomiting & diarrhea

Question 20

pt has sores from picking at it. what drug abuse

Answer 20

meth

Question 21

Phenytoin (Dilantin) SE

Answer 21

Gingival Hyperplasia

Question 22

OD Iron

Answer 22

GI Bleed
uncouples ox-phos
deposits in brain, heart, lungs
hepatic liver failure

Question 23

Fe overdose tx

Answer 23

deferoxime

Question 24

what age for doxy

Answer 24

older than 8

Question 25

tx for Bronchiolitis (RSV)

Answer 25

Pavilizumab

Question 26

tx for trans-placental Graves

Answer 26

give baby Methimazole or B-blockers. Resolves after mother’s Ab go away.

Question 27

Reye syndrome

Answer 27

microvesicular fatty infiltration of liver causing

elevated LFTs
encephalopathy
elevated PT and PTT
hyperamonemia

Question 28

Rocephin

Answer 28

interferes with bilirubin binding to albumin

Question 29

Formeterol

Answer 29

long acting B2

Question 30

Amphetamine OD tx

Answer 30

Benzos

Question 31

Valproic Acid does what to eyes

Answer 31

infra-orbital creases

Question 32

Warfarin does what to face

Answer 32

nasal hypoplasia