Peds Endocrine Flashcards
Central Incisor in Newborn?
Hypothyroidism
Normal adolescence what age
9
Rotterdam Criteria
for PCOS 2/3 1. Oligo/Anovulation 2. Signs of Hyperadrongenism 3. Polycystic Ovaries Metabolic syndrome common in PCOS
sugar and osmolar gap
Na drops 1.6 for every 100 glucose over 100
Test for CAH
17-hydroxyprogesterone is elevated in 21- and 11- hydroxylase deficiency and decreased in 17-hydroxylase deficiency
prolactin inhibits
GNRH
MCC CAH deficiency
21B Hydroxylase def
what is difference between 21-hydroxylase def and 11B-hydroxylase def
11B-deficiency has elevated 11 Deoxycortisol. 21-hydroxylase def does not 11 = salt retention (11 deoxycortisol is potent) 21 = salt wasting high K
Commonalities in 21 and 11-hydroxylase deficiency
Ambiguous genitalia in girls
failure to thrive and poor feeding
Hypothyroidism
Premature Adrenarce
caused by early activation of adrenal androgen release
Central vs. Peripheral Precocious Puberty algorithm
MCC primary hyperparathydroid
Parathyroid Adenoma
congenital hypothyroidism
apathy,
weakness,
hypotonia,
large tongue,
sluggish movement
abdominal bloating
umbilical hernia
(wtf, I know)