Peds Endocrine Flashcards
Central Incisor in Newborn?
Hypothyroidism
Normal adolescence what age
9
Rotterdam Criteria
for PCOS 2/3 1. Oligo/Anovulation 2. Signs of Hyperadrongenism 3. Polycystic Ovaries Metabolic syndrome common in PCOS
sugar and osmolar gap
Na drops 1.6 for every 100 glucose over 100
Test for CAH
17-hydroxyprogesterone is elevated in 21- and 11- hydroxylase deficiency and decreased in 17-hydroxylase deficiency
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prolactin inhibits
GNRH
MCC CAH deficiency
21B Hydroxylase def
what is difference between 21-hydroxylase def and 11B-hydroxylase def
11B-deficiency has elevated 11 Deoxycortisol. 21-hydroxylase def does not 11 = salt retention (11 deoxycortisol is potent) 21 = salt wasting high K
Commonalities in 21 and 11-hydroxylase deficiency
Ambiguous genitalia in girls
failure to thrive and poor feeding
Hypothyroidism
Premature Adrenarce
caused by early activation of adrenal androgen release
Central vs. Peripheral Precocious Puberty algorithm
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MCC primary hyperparathydroid
Parathyroid Adenoma
congenital hypothyroidism
apathy,
weakness,
hypotonia,
large tongue,
sluggish movement
abdominal bloating
umbilical hernia
(wtf, I know)