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Peds Clerkship > Peds Heme/Onc > Flashcards

Peds Heme/Onc Flashcards

1
Q

Neutrophilia with lots of bands (>700)

A

neonatal sepsis

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2
Q

kidney disease associated with HIV

A

FSGS - most common nephrotic syndrome in adults

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3
Q

Hep B kidney disease

A

Membranous nephropathy (nephrotic)

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4
Q

pre-adolescent kidney disease

A

minimal change disease

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5
Q

PSGN

A

nephritic

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6
Q

Blood transufsions what electrolyte abnormality

A

Fe overload

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7
Q

Reticulocyclopenia

from what infx

A

sudden arrest of erythropoesis

parvo B19

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8
Q

Hemophilia A &B inheritance patten

A

X-linked recessive

usually males

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9
Q

Parvo risk in sickle cell

A

aplastic anemia

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10
Q

Shield Chest

A

Diamond Blackfan,
Noonan
Turner Syndrome

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11
Q

ITP tx

A

glucocorticoids or IVIG

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12
Q

Wiskott Aldrich triad

A

X-linked disorder with

  1. thrombocytopenia
  2. eczema
  3. recurrent bacterial infx
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13
Q

ALL

A

Hepatospleenomegally
lymphadenopathy
petichiae

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14
Q

nasal obstruction with visible mass
bony errosion
epistaxis

A

Juvenile angiofibroma

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15
Q

Juvenile angiofibroma

A

nasal obstruction with visible mass
bony errosion
epistaxis

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16
Q

renal failure
hemolytic anemia
thrombocytopenia

s/p diarrhea

A

Hemolytic Anemia

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17
Q

Diamond Blackfan anemia vs. Megaloblastic

A

Both are Macrocytic

Diamond Blackfan results in no hypersegmentation of nucleus in neutrophils

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18
Q

Macrocytic Anemia with Congenital anomalies and low retic count

A

Diamond Blackfan anemia

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19
Q

Diamond Blackfan anemia tx

A

corticosteroids/ transfusions

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20
Q

Wiskott-Aldrich inheritence

A

X-linked

21
Q

Eczema
Low Platelets
Hypgammaglobulinemia

A

Wiskott-Aldrich

22
Q

Red Cell Aplasia

A

Transient Erythroblastopenia

23
Q

Pancytopenia and Macrocytosis and

Cafe Au Lait spots, microcephaly, horshoe kidneys, no thumbs (not triphalangeal thumbs)

A

Fanconis

24
Q

Fanconis

A

Pancytopenia and Macrocytosis and

Cafe Au Lait spots, microcephaly, horshoe kidneys, no thumbs (not triphalangeal thumbs)

25
Q

Fanconi’s age

A

8 years

26
Q

Diamond Blackfan anomalies

A

Sheild Chest, Triphalangeal thumbs, short with webbed neck and cleft lip

27
Q

Heinz bodies

A

hemoglobin precipitates… found in G6PD deficiency

28
Q

low Retic

A

Fe def, B12 def, chemo, infx, aplastic anemia

29
Q

neonatal polycythemia

A

delayed clamping of umbilical cord

May cause respiratory distress, hypoglycemia

Hct>65%

30
Q

Leukocytosis
Anemia
Thrombocytopenia

A

ALL

Pain insidious and worse at night

31
Q

Pancytopenia after drugs or toxin exposure or viral infections

A

Aplastic Anemia

32
Q 
anemia
hyperpigmentation on trunk and intertrigenous areas
cafe au lait
short stature
hypogonads
renal changes
eyelid changes
A

Fanconis

Thrombocytopenia is first then neutropenia then anemia

33
Q

Diamond Blackfan age

A

first 3 months of life

34
Q

Transient Erythroblastopenia of Childhood (TEC)

A

acquired aplastic anemia

gradual pallor and tachycardia

normocytic normochromic anemia

35
Q

prolonged aPTT but not PT in newborn

A

Factor 8 def (similar to vWD)

36
Q

mucocutaneous bleeding
petechiae
normal PT, normal aPTT

A

uremia
aspirin/clopidogrel

Glanzmann throbasthenia congenital disorder

37
Q

MCC inherited bleeding d/o

A

von Willebrand dz

may present similar to Factor 8 def

38
Q

prolonged PT and aPTT in newborn

A

think Vitamin K def

39
Q

hypochromic microcytic anemia with family hx

A

Alpha Thal

40
Q

hypochromic microcytic anemia from 6-12 months

A

Beta Thal

41
Q

Hemophilia A

A

Factor 8

42
Q

Hemophilia B

A

Factor 9

43
Q

Fe deficiency vs. spherocytosis

A

Fe deficiency has increased RDW

44
Q

vitamin K clotting factors

A

2, 7, 9, 10, Protein C, Protein S

45
Q

how to diagnose ALL

A

bone marrow biopsy

46
Q

Anisocytosis

A

red blood cells of different size common in Fe def. anemia

47
Q

what is normal level of reticulocytes

A

0.5% - 1.5%

48
Q

low retic vs. high retic

A

low retic = leukemia or infection or aplastic anemia

high retic = hemolysis or maybe hemorrhage

Peds Clerkship (17 decks)

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